Powder: -20°C for 3 years | In solvent: -80°C for 1 year
9-hydroxy Stearic Acid is a hydroxy fatty acid that is the active metabolite of 9-PAHSA. 9-hydroxy Stearic Acid is formed from 9-PAHSA through carboxyl ester lipase in the liver and pancreas. The 9-hydroxy Stearic Acid (5 μM) was stearic acid, which inhibited the expression of histone deacetylase 1 (HDAC1) in the lysate of HT-29 colon cancer cells. 3. When the concentration was 100 μM.1, the proliferation of HT-29 cells was inhibited and cell cycle arrest was induced in G0/ g1 phase.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 39.00 | |
5 mg | In stock | $ 172.00 | |
10 mg | In stock | $ 297.00 | |
25 mg | In stock | $ 492.00 | |
50 mg | In stock | $ 718.00 | |
100 mg | In stock | $ 987.00 |
Description | 9-hydroxy Stearic Acid is a hydroxy fatty acid that is the active metabolite of 9-PAHSA. 9-hydroxy Stearic Acid is formed from 9-PAHSA through carboxyl ester lipase in the liver and pancreas. The 9-hydroxy Stearic Acid (5 μM) was stearic acid, which inhibited the expression of histone deacetylase 1 (HDAC1) in the lysate of HT-29 colon cancer cells. 3. When the concentration was 100 μM.1, the proliferation of HT-29 cells was inhibited and cell cycle arrest was induced in G0/ g1 phase. |
In vitro |
9-hydroxy Stearic acid is a hydroxy fatty acid and an active metabolite of 9-PAHSA .[1][2] It is formed from 9-PAHSA by liver and pancreatic carboxyl ester lipases.2 9-hydroxy Stearic acid (5 µM) inhibits histone deacetylase 1 (HDAC1) in HT-29 colon cancer cell lysates.[3] It inhibits the proliferation of, and induces cell cycle arrest at the G0/G1 phase in, HT-29 cells when used at a concentration of 100 µM.1.[1] |
Molecular Weight | 300.48 |
Formula | C18H36O3 |
CAS No. | 3384-24-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chloroform: Soluble
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9-hydroxy Stearic Acid 3384-24-5 Chromatin/Epigenetic DNA Damage/DNA Repair HDAC 9 hydroxy Stearic Acid 9hydroxy Stearic Acid inhibitor inhibit