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Deltonin

Name: Deltonin
Brand: TargetMol
SKU: T3844
Price: 98 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3844Cas No. 55659-75-1

Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 μM), mouse C26 cells (IC50: 1.22 μM), and human MDA-MB-231 cells (IC50: 1.58 μM).

Deltonin

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Purity: 99.79%

Catalog No. T3844Cas No. 55659-75-1

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$98	In Stock	In Stock
5 mg	$263	In Stock	In Stock
10 mg	$396	-	In Stock
25 mg	$648	-	In Stock
50 mg	$912	-	In Stock
1 mL x 10 mM (in DMSO)	$386	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.79%

Appearance:Solid

Color:White

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Product Introduction

Deltonin AI Summary

Deltonin exhibits cytotoxicity against various cell lines including human HepG2, mouse C26, human MDA-MB-231, and human NCI-H460 cells. The cytotoxic effects were measured using the MTT assay. After 48 hours, the IC50 values were 7660.0 nM for HepG2, 1220.0 nM for C26, and 1580.0 nM for MDA-MB-231 cells. Additionally, after 24 hours, the IC50 value for NCI-H460 cells was 5810.0 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 μM), mouse C26 cells (IC50: 1.22 μM), and human MDA-MB-231 cells (IC50: 1.58 μM).
Targets&IC50	HepG2 cells:7.66 μM, MDA-MB-231 cells (human):1.58 μM, C26 cells (mouse):1.22 μM

Chemical Properties

Molecular Weight	885.04
Formula	C₄₅H₇₂O₁₇
Cas No.	55659-75-1
Smiles	[H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@H](CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]1(CC[C@@H](C)CO1)O2)O[C@]1([H])O[C@H](CO)[C@@H](O[C@]2([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@]1([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O
Relative Density.	1.42 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 100 mg/mL (112.99 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.1299 mL	5.6495 mL	11.2989 mL	56.4946 mL
5 mM	0.2260 mL	1.1299 mL	2.2598 mL	11.2989 mL
10 mM	0.1130 mL	0.5649 mL	1.1299 mL	5.6495 mL
20 mM	0.0565 mL	0.2825 mL	0.5649 mL	2.8247 mL
50 mM	0.0226 mL	0.1130 mL	0.2260 mL	1.1299 mL
100 mM	0.0113 mL	0.0565 mL	0.1130 mL	0.5649 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc