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Synonyms: RR1, RIR1, ribonucleotide reductase M1, R1

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $199 | 7-10 days | 7-10 days |
| Description | Anti-RRM1 Antibody (3D202) is a Mouse antibody targeting RRM1. Anti-RRM1 Antibody (3D202) can be used in FCM,ICC/IF. |
| Synonyms | RR1, RIR1, ribonucleotide reductase M1, R1 |
| Ig Type | Mouse IgG1 |
| Clone | 3D202 |
| Reactivity | Human |
| Specificity | Human RRM1 |
| Application | |
| Recommended Dose | ICC-IF: 1:20-1:100; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RRM1 (rh RRM1; TMPY-03287; P23921; Met1-Ser792). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | RRM1 is a subunit of ribonucleoside-diphosphate reductase which is constituted by two subunits. Ribonucleoside-diphosphate reductase is an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. RRM1 is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. RRM1 may play a role in malignancies and disease that involve this region. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human RRM1 protein (TMPY-03287) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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