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Anti-FOS Antibody (4X378)
(Synonyms: Proto-oncogene c-Fos, p55, Oncogene FOS, G0S7, G0/G1 switch regulatory protein 7, FBJ Osteosarcoma Virus, FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS), Cellular oncogene c fos, C FOS, AP 1, Activator protein 1) Copy Product Info
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Synonyms: Proto-oncogene c-Fos, p55, Oncogene FOS, G0S7, G0/G1 switch regulatory protein 7, FBJ Osteosarcoma Virus, FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS), Cellular oncogene c fos, C FOS, AP 1, Activator protein 1
Catalog No. TMAB-00697 Copy Product Info
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Anti-FOS Antibody (4X378) is a Mouse antibody targeting FOS. Anti-FOS Antibody (4X378) can be used in WB.
Anti-FOS Antibody
(4X378)
(4X378)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-FOS Antibody (4X378) is a Mouse antibody targeting FOS. Anti-FOS Antibody (4X378) can be used in WB. |
| Synonyms | Proto-oncogene c-Fos, p55, Oncogene FOS, G0S7, G0/G1 switch regulatory protein 7, FBJ Osteosarcoma Virus, FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS), Cellular oncogene c fos, C FOS, AP 1, Activator protein 1 |
| Ig Type | IgG |
| Clone | 4X378 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Nucleus. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]. |
| Immunogen | Recombinant Protein: human c-fos Protein |
| Antigen Species | Human |
| Gene Name | FOS |
| Gene ID | |
| Protein Name | Proto-oncogene c-Fos |
| Uniprot ID | |
| Biology Area | Transcription factors,Oncoproteins,Proto-oncogenes,Leucine Zipper,Soma marker |
| Function | Nuclear phosphoprotein which forms a tight butnon-covalently linked complex with the JUN/AP-1 transcriptionfactor. In the heterodimer, FOS and JUN/AP-1 basic regions eachseems to interact with symmetrical DNA half sites. On TGF-betaactivation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at theAP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Hasa critical function in regulating the Has a critical function inregulating the development of cells destined to form and maintainthe skeleton. It is thought to have an important role in signaltransduction, cell proliferation and differentiation. |
| Molecular Weight | Theoretical: 41 kDa. Actual: 50 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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