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beta-Amyrin acetate
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Catalog No. TN1438Cas No. 1616-93-9
beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, and anti-hyperlipidemic activities.
beta-Amyrin acetate
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Purity: 99.87%
Catalog No. TN1438Cas No. 1616-93-9
beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, and anti-hyperlipidemic activities.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $59 | In Stock | In Stock | |
| 5 mg | $143 | In Stock | In Stock | |
| 10 mg | $189 | In Stock | In Stock | |
| 25 mg | $318 | In Stock | In Stock | |
| 50 mg | $473 | In Stock | In Stock | |
| 100 mg | $678 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.87%
Appearance:Solid
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, and anti-hyperlipidemic activities. |
| In vitro | beta-Amyrin acetate (25 μM) decreases mEH activity to 61% of control activity[1]. beta-Amyrin acetate (50 μg/mL) inhibits heat-induced hemolysis and hypotonicity-induced hemolysis of human erythrocytes[2]. beta-Amyrin acetate (7.8-1000 μg/mL) inhibits all of the Candida fungal species tested (MIC: 30 - 250 μg/mL)[5]. |
| In vivo | In Xylene-induced mouse ear topical edema model, beta-Amyrin acetate (100 μg/ear) significantly inhibits xylene-induced ear edema[2]. In normal and arthritic rats, beta-Amyrin acetate (40 mg/kg; s.c.) increases the ATP-phosphohydrolase activity in liver homogenates. In adult albino rats, beta-Amyrin acetate (40 mg/kg; i.p.) shows significant anti-inflammatory activities to 43.6% with mean average weight of granulation tissue of 9.2 mg after 6 days[4]. |
| Molecular Weight | 468.75 |
| Formula | C32H52O2 |
| Cas No. | 1616-93-9 |
| Smiles | [H][C@@]12CC(C)(C)CC[C@]1(C)CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OC(C)=O)C(C)(C)[C@]3([H])CC[C@@]12C |
| Relative Density. | 1.02g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: < 1 mg/mL (insoluble)  DMSO: < 1 mg/mL (insoluble) Ethanol: < 1 mg/mL (insoluble) |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
β-Amyrin Acetateβ-AmyrinsEHLDLInhibitorinhibitinflammationImmunology & Inflammation relatedHMGCoAReductaseHMG-CoA Reductase (HMGCR)HMGCoA ReductaseHMG-CoAhemolysisFungalEpoxideHydrolaseEpoxide Hydrolasebeta-Amyrin AcetatebetaAmyrin acetatebeta Amyrin acetateb-Amyrin AcetatearthriticAntioxidantanti-inflammatoryAntifungal
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