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M617 acetate is a selective agonist of galanin receptor 1 (GAL1). M617 acetate acts through central GAL1, promotes GLUT4 expression, and enhances GLUT4 content in the cardiac muscle of type 2 diabetic rats. The Ki values are 0.23 and 5.71 nM for GAL1 and GAL2, respectively.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $102 | - | In Stock | |
| 5 mg | $223 | - | In Stock | |
| 10 mg | $378 | - | In Stock | |
| 25 mg | $643 | - | In Stock | |
| 50 mg | $963 | - | In Stock | |
| 100 mg | $1,390 | - | In Stock | |
| 200 mg | $2,050 | - | In Stock |
| Description | M617 acetate is a selective agonist of galanin receptor 1 (GAL1). M617 acetate acts through central GAL1, promotes GLUT4 expression, and enhances GLUT4 content in the cardiac muscle of type 2 diabetic rats. The Ki values are 0.23 and 5.71 nM for GAL1 and GAL2, respectively. |
| Targets&IC50 | GAL1:0.23 nM(Ki), GAL2:5.71 nM(Ki) |
| Molecular Weight | 2361.65 |
| Formula | C112H161N29O28 |
| Smiles | CC(C)C[C@@H](C(NCC(N(CCC1)[C@@H]1C(N[C@@H](CCC(N)=O)C(N(CCC1)[C@@H]1C(N(CCC1)[C@@H]1C(NCC(N[C@@H](Cc1ccccc1)C(N[C@@H](CO)C(N(CCC1)[C@@H]1C(N[C@@H](Cc1ccccc1)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CC(C)C)NC([C@H](Cc(cc1)ccc1O)NC(CNC([C@H](C)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)O)NC([C@H](Cc1c[nH]c2c1cccc2)NC(CN)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O |
| Sequence | Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Gln-Pro-Pro-Gly-Phe-Ser-Pro |
| Sequence Short | GWTLNSAGYLLGPQPPGFSPFR |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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