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(R)-Elexacaftor

Catalog No. T78240 CAS 2229860-99-3

Synonyms: (R)-VX-445

(R)-Elexacaftor, an enantiomer of Elexacaftor, functions as a modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It exhibits an EC50 of 0.29 µM for the CFTR dF508 mutation [1].

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(R)-Elexacaftor, CAS 2229860-99-3

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	(R)-VX-445
Molecular Weight	597.65
Formula	C26H34F3N7O4S
CAS No.	2229860-99-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Related Products

Related compounds with same targets

CFTR corrector 9 (R)-BPO-27 PPQ-102 DNDS Cavosonstat IOWH-032 KM11060 Glibenclamide

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

(R)-Elexacaftor 2229860-99-3 Membrane transporter/Ion channel CFTR (R)-VX-445 VX445 VX-445 VX 445 Elexacaftor inhibitor inhibit

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