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L-Glyceric acid sodium

Catalog No. T38954 CAS 146298-95-5

L-Glyceric acid sodium is a urinary metabolite predominantly found in individuals with the rare inherited metabolic disorder, L-glyceric aciduria. This compound serves as a diagnostic tool for identifying primary hyperoxaluria type 2 (PH2) and can be used to differentiate between PH1 and PH2 based on its excretion pattern.

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L-Glyceric acid sodium Chemical Structure

L-Glyceric acid sodium, CAS 146298-95-5

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Storage & Solubility Information

Description	L-Glyceric acid sodium is a urinary metabolite predominantly found in individuals with the rare inherited metabolic disorder, L-glyceric aciduria. This compound serves as a diagnostic tool for identifying primary hyperoxaluria type 2 (PH2) and can be used to differentiate between PH1 and PH2 based on its excretion pattern.
In vitro	Primary hyperoxaluria type 2 (PH2), also referred to as L-glyceric aciduria, results from deficiencies in D-glycerate dehydrogenase and glyoxylate reductase. These enzyme deficiencies culminate in the excretion of L-glyceric acid, which serves as a critical diagnostic marker for PH2[1][2].

Molecular Weight	129.067
Formula	C3H6NaO4
CAS No.	146298-95-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Mohamed S Rashed, et al. Chiral liquid chromatography tandem mass spectrometry in the determination of the configuration of glyceric acid in urine of patients with D-glyceric and L-glyceric acidurias. Biomed Chromatogr. 2002 May;16(3):191-8. 2. Bernd Hoppe, et al. A United States survey on diagnosis, treatment, and outcome of primary hyperoxaluria. Pediatr Nephrol. 2003 Oct;18(10):986-91.

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Keywords

L-Glyceric acid sodium 146298-95-5 LGlyceric acid sodium L Glyceric acid sodium inhibitor inhibit

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