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Anti-GCG Antibody (5D789) (Synonyms: Oxyntomodulin, OXY, OXM, Incretin Hormone, GRPP, Glucagon-Like Peptide...)

Catalog No. TMAH-00478 Copy Product Info
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Anti-GCG Antibody (5D789) is an antibody targeting GCG. Anti-GCG Antibody (5D789) can be used in ELISA.

Anti-GCG Antibody (5D789)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00478
Synonyms Oxyntomodulin, OXY, OXM, Incretin Hormone, GRPP, Glucagon-Like Peptide 2, Glucagon-Like Peptide 1, Glucagon, GLP-2, GLP-1, Glicentin-Related Polypeptide, Glicentin, GCG

Anti-GCG Antibody (5D789) is an antibody targeting GCG. Anti-GCG Antibody (5D789) can be used in ELISA.

Anti-GCG Antibody
(5D789)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3487-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GCG Antibody (5D789) is an antibody targeting GCG. Anti-GCG Antibody (5D789) can be used in ELISA.
SynonymsOxyntomodulin, OXY, OXM, Incretin Hormone, GRPP, Glucagon-Like Peptide 2, Glucagon-Like Peptide 1, Glucagon, GLP-2, GLP-1, Glicentin-Related Polypeptide, Glicentin, GCG
Ig Type
Rabbit IgG
Clone
5D789
Reactivity
Human
Application
Antibody Type
Monoclonal
Subcellular LocalizationSecreted.; [Glucagon-like peptide 1]: Secreted.
Tissue Specificity[Glucagon]: Secreted in the A cells of the islets of Langerhans.; [Glucagon-like peptide 1]: Secreted in the A cells of the islets of Langerhans. Secreted from enteroendocrine L cells throughout the gastrointestinal tract. Also secreted in selected neuron
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundPlays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. Potent stimulator of glucose-dependent insulin release. Also stimulates insulin release in response to IL6. Plays important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Has growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion. Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation. Inhibits beta cell apoptosis. Stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability. Significantly reduces food intake. Inhibits gastric emptying in humans. Suppression of gastric emptying may lead to increased gastric distension, which may contribute to satiety by causing a sensation of fullness. May modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human GCG
Antigen Species
Human
Gene Name
GCG
Gene ID
Uniprot ID
Biology Area
Signal Transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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