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Anti-GCG Antibody (5D789)

😃Good
Catalog No. TMAH-00478
Alias Oxyntomodulin, OXY, OXM, Incretin Hormone, GRPP, Glucagon-Like Peptide 2, Glucagon-Like Peptide 1, Glucagon, GLP-2, GLP-1, Glicentin-Related Polypeptide, Glicentin, GCG

Anti-GCG Antibody (5D789) is an antibody targeting GCG. Anti-GCG Antibody (5D789) can be used in ELISA.

Anti-GCG Antibody (5D789)

Anti-GCG Antibody (5D789)

😃Good
Catalog No. TMAH-00478Alias Oxyntomodulin, OXY, OXM, Incretin Hormone, GRPP, Glucagon-Like Peptide 2, Glucagon-Like Peptide 1, Glucagon, GLP-2, GLP-1, Glicentin-Related Polypeptide, Glicentin, GCG
Anti-GCG Antibody (5D789) is an antibody targeting GCG. Anti-GCG Antibody (5D789) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
50 μL196 € 7-10 days
100 μL330 € 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Monoclonal

Application: ELISA

Reactivity: Human
AliasOxyntomodulin, OXY, OXM, Incretin Hormone, GRPP, Glucagon-Like Peptide 2, Glucagon-Like Peptide 1, Glucagon, GLP-2, GLP-1, Glicentin-Related Polypeptide, Glicentin, GCG
Ig Type
Rabbit IgG
Clone
5D789
Reactivity
Human
Application
ELISA
Antibody Type
Monoclonal
Subcellular LocalizationSecreted.; [Glucagon-like peptide 1]: Secreted.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundPlays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. Potent stimulator of glucose-dependent insulin release. Also stimulates insulin release in response to IL6. Plays important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Has growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion. Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation. Inhibits beta cell apoptosis. Stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability. Significantly reduces food intake. Inhibits gastric emptying in humans. Suppression of gastric emptying may lead to increased gastric distension, which may contribute to satiety by causing a sensation of fullness. May modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human GCG
Antigen Species
Human
Gene ID
2641
Uniprot ID
Biology Area
Signal Transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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