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Dammarenediol II
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Catalog No. TN5942Cas No. 14351-29-2
Alias Dammar-24-ene-3,20-diol
Dammarenediol II may exert protective effects against diabetic microvascular complications, including diabetic retinopathy, by potently inhibiting vascular endothelial growth factor (VEGF)-induced intracellular reactive oxygen species generation, stress fiber formation, and vascular endothelial cadherin disruption. Dammarenediol II preserves endothelial integrity, this medicinally important triterpenoid can be ectopically produced in tobacco, where dammarenediol II biosynthesis enables plants to adopt a virus-resistance defense system, supporting its relevance in metabolic disease research, vascular biology, and plant-based bioproduction strategies.
Dammarenediol II
😃Good
Purity: 99.77%
Catalog No. TN5942Alias Dammar-24-ene-3,20-diolCas No. 14351-29-2
Dammarenediol II may exert protective effects against diabetic microvascular complications, including diabetic retinopathy, by potently inhibiting vascular endothelial growth factor (VEGF)-induced intracellular reactive oxygen species generation, stress fiber formation, and vascular endothelial cadherin disruption. Dammarenediol II preserves endothelial integrity, this medicinally important triterpenoid can be ectopically produced in tobacco, where dammarenediol II biosynthesis enables plants to adopt a virus-resistance defense system, supporting its relevance in metabolic disease research, vascular biology, and plant-based bioproduction strategies.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $197 | - | In Stock | |
| 5 mg | $488 | - | In Stock | |
| 10 mg | $778 | - | In Stock | |
| 25 mg | $1,160 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.77%
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Dammarenediol II may exert protective effects against diabetic microvascular complications, including diabetic retinopathy, by potently inhibiting vascular endothelial growth factor (VEGF)-induced intracellular reactive oxygen species generation, stress fiber formation, and vascular endothelial cadherin disruption. Dammarenediol II preserves endothelial integrity, this medicinally important triterpenoid can be ectopically produced in tobacco, where dammarenediol II biosynthesis enables plants to adopt a virus-resistance defense system, supporting its relevance in metabolic disease research, vascular biology, and plant-based bioproduction strategies. |
| Synonyms | Dammar-24-ene-3,20-diol |
| Molecular Weight | 444.74 |
| Formula | C30H52O2 |
| Cas No. | 14351-29-2 |
| Smiles | C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](O)CC3)[H])(CC[C@]4([C@@]2(C)CC[C@@]4([C@@](CCC=C(C)C)(C)O)[H])[H])[H] |
| Relative Density. | 0.993 g/cm3 (Predicted) |
| Color | White |
| Appearance | Solid |
| Storage | keep away from direct sunlight | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 8 mg/mL (17.99 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyThe above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
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