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Br-C3-methyl ester
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Catalog No. T40574Cas No. 4897-84-1
Alias Br-C3-methyl ester
Br-C3-methyl ester is an alkyl/ether-based PROTAC linker utilized for the synthesis of PROTAC PD-1/PD-L1 degrader-1.
Br-C3-methyl ester
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Catalog No. T40574Alias Br-C3-methyl esterCas No. 4897-84-1
Br-C3-methyl ester is an alkyl/ether-based PROTAC linker utilized for the synthesis of PROTAC PD-1/PD-L1 degrader-1.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 500 mg | $42 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | Br-C3-methyl ester is an alkyl/ether-based PROTAC linker utilized for the synthesis of PROTAC PD-1/PD-L1 degrader-1. |
| In vitro | PROTACs, composed of two distinct ligands connected by a linker—one binding to an E3 ubiquitin ligase and the other to the target protein—utilize the ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| Synonyms | Br-C3-methyl ester |
| Molecular Weight | 181.03 |
| Formula | C5H9BrO2 |
| Cas No. | 4897-84-1 |
| Relative Density. | 1.434 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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