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Anti-NRG1 Beta 1 Antibody (1T318)

😃Good
Catalog No. TMAY-00060
Alias SMDF, NRG1-IT2, NRG1 β1, Neuregulin 1, NDF, MSTP131, MST131, HRGA, HRG1, HRG, HGL, GGF2, GGF, ARIA

Anti-NRG1 Beta 1 Antibody (1T318) is a Mouse antibody targeting NRG1 Beta 1. Anti-NRG1 Beta 1 Antibody (1T318) can be used in WB.

Anti-NRG1 Beta 1 Antibody (1T318)

Anti-NRG1 Beta 1 Antibody (1T318)

😃Good
Catalog No. TMAY-00060Alias SMDF, NRG1-IT2, NRG1 β1, Neuregulin 1, NDF, MSTP131, MST131, HRGA, HRG1, HRG, HGL, GGF2, GGF, ARIA
Anti-NRG1 Beta 1 Antibody (1T318) is a Mouse antibody targeting NRG1 Beta 1. Anti-NRG1 Beta 1 Antibody (1T318) can be used in WB.
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100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-NRG1 Beta 1 Antibody (1T318) is a Mouse antibody targeting NRG1 Beta 1. Anti-NRG1 Beta 1 Antibody (1T318) can be used in WB.
AliasSMDF, NRG1-IT2, NRG1 β1, Neuregulin 1, NDF, MSTP131, MST131, HRGA, HRG1, HRG, HGL, GGF2, GGF, ARIA
Ig Type
Monoclonal Mouse IgG2b
Clone
1T318
Reactivity
Human
Verified Activity
Anti-NRG1-beta 1 mouse monoclonal antibody at 1:500Lane A: Human NRG1-beta1 (100ng)

-Lane B: Human NRG1-alpha (100ng)

-Secondary

-Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution.

-Performed under reducing conditions.
Application
WB
Recommended Dose
WB: 1:500-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, a synthetic peptide corresponding to the center region of the human NRG1 isoform beta 1. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundNeuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. NRG1 is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by the usage of different promoters and alternative splicing of a single gene. Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. NRG1 is a schizophrenia candidate gene and plays an important role in brain development and neural function. Schizophrenia is a complex disorder, with etiology likely due to epistasis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
A synthetic peptide corresponding to the center region of the human NRG1 isoform beta 1.
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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