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3-Methoxytyramine

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Catalog No. T8269Cas No. 554-52-9
Alias 3-O-methyl Dopamine

3-Methoxytyramine (3-O-methyl Dopamine) is a cellular metabolite of dopamine (3-hydroxytyramine), a neuromodulator that induces behavioral effects, induces significant ERK and CREB phosphorylation, and is capable of inducing a complex set of aberrant involuntary movements in acutely depleted dopamine-containing mice.

3-Methoxytyramine
Other Forms of 3-Methoxytyramine:
3-Methoxytyramine hydrochlorideT47101477-68-5
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3-Methoxytyramine

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Purity: 99.42%
Catalog No. T8269Alias 3-O-methyl DopamineCas No. 554-52-9
3-Methoxytyramine (3-O-methyl Dopamine) is a cellular metabolite of dopamine (3-hydroxytyramine), a neuromodulator that induces behavioral effects, induces significant ERK and CREB phosphorylation, and is capable of inducing a complex set of aberrant involuntary movements in acutely depleted dopamine-containing mice.
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50 mg$32In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.42%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
3-Methoxytyramine (3-O-methyl Dopamine) is a cellular metabolite of dopamine (3-hydroxytyramine), a neuromodulator that induces behavioral effects, induces significant ERK and CREB phosphorylation, and is capable of inducing a complex set of aberrant involuntary movements in acutely depleted dopamine-containing mice.
In vivo
3-Methoxytyramine, an extracellular metabolite of dopamine (DA), was able to elicit significant behavioral responses in dopamine-deficient DAT-KO (DDD) mice. In addition, 3-Methoxytyramine promotes behavioral responses in dopamine-deficient mice by activating intracellular signaling pathways in the striatum. [1]
Synonyms3-O-methyl Dopamine
Chemical Properties
Molecular Weight167.21
FormulaC9H13NO2
Cas No.554-52-9
SmilesOC1=CC=C(C=C1OC)CCN
Relative Density.1.126 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from moisture,store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 1 mg/mL (5.98 mM), Sonication is recommended.
H2O: 4 mg/mL (23.92 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM5.9805 mL29.9025 mL59.8050 mL299.0252 mL
5 mM1.1961 mL5.9805 mL11.9610 mL59.8050 mL
H2O
1mg5mg10mg50mg
10 mM0.5981 mL2.9903 mL5.9805 mL29.9025 mL
20 mM0.2990 mL1.4951 mL2.9903 mL14.9513 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

EndogenousMetaboliteEndogenous Metabolite3-Methoxytyramine3Methoxytyramine3 Methoxytyramine
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