Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AK-2292 is a potent and selective STAT5 PROTAC degrader, with a DC 50 of 0.10 μM. AK-2292 induces degradation of STAT5A/B proteins in vitro and in vivo. AK-2292 can induce tumor regression in acute myeloid leukemia and chronic myeloid leukemia xenograft mouse models [1] [2] .
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50 mg | Inquiry | Inquiry |
Description | AK-2292 is a potent and selective STAT5 PROTAC degrader, with a DC 50 of 0.10 μM. AK-2292 induces degradation of STAT5A/B proteins in vitro and in vivo. AK-2292 can induce tumor regression in acute myeloid leukemia and chronic myeloid leukemia xenograft mouse models [1] [2] . |
Molecular Weight | 1070.13 |
Formula | C52H54F2N7O10PS2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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AK-2292 PROTAC PROTACs inhibitor inhibit