store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HS-276 is a highly selective, orally active inhibitor of TAK1 (Ki: 2.5 nM). HS-276 significantly inhibits TAK1 (IC50: 8.25 nM), CLK2 (IC50: 29 nM), GCK (IC50: 22 nM), ULK2 (IC50: 63 nM), MAP4K5 (IC50. HS-276 can be used to study rheumatoid arthritis (RA).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 91.00 | |
5 mg | In stock | $ 213.00 | |
10 mg | In stock | $ 333.00 | |
25 mg | In stock | $ 588.00 | |
50 mg | In stock | $ 855.00 | |
100 mg | In stock | $ 1,180.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 235.00 |
Description | HS-276 is a highly selective, orally active inhibitor of TAK1 (Ki: 2.5 nM). HS-276 significantly inhibits TAK1 (IC50: 8.25 nM), CLK2 (IC50: 29 nM), GCK (IC50: 22 nM), ULK2 (IC50: 63 nM), MAP4K5 (IC50. HS-276 can be used to study rheumatoid arthritis (RA). |
Targets&IC50 | NUAK:270 nM, CaMKK β1:1280 nM, MAP4K5:125 nM, TAK1:8.25 nM, TAK1:2.5 nM (Ki), ULK2:63 nM, GCK:33 nM, CLK2:29 nM, CSNK1G2:810 nM, MLK1:5585 nM, IRAK1:264 nM |
Molecular Weight | 419.52 |
Formula | C24H29N5O2 |
CAS No. | 2767422-72-8 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45.0 mg/mL (107.3 mM), when pH is adjusted to 2 with HCl. Sonication and heating to 80℃ are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
HS-276 2767422-72-8 MAPK inhibitor inhibit