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Dalbavancin

🥰Excellent
Catalog No. T21358Cas No. 171500-79-1
Alias VER-001, VER 001, BI-397, BI397, BI 397, A-A-1 antibiotic

Dalbavancin (BI-397), a novel second-generation lipoglycopeptide antibiotic, possesses in vitro activity against a variety of Gram-positive pathogens including methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE),Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively

Dalbavancin
Other Forms of Dalbavancin:
Dalbavancin hydrochlorideT752532227366-51-8
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Dalbavancin

🥰Excellent
Purity: 99.09%
Catalog No. T21358Alias VER-001, VER 001, BI-397, BI397, BI 397, A-A-1 antibioticCas No. 171500-79-1
Dalbavancin (BI-397), a novel second-generation lipoglycopeptide antibiotic, possesses in vitro activity against a variety of Gram-positive pathogens including methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE),Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$55In StockIn Stock
5 mg$129In StockIn Stock
10 mg$195In StockIn Stock
25 mg$393In StockIn Stock
50 mg$591In StockIn Stock
100 mg$843In StockIn Stock
1 mL x 10 mM (in DMSO)$205In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.09%
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Product Introduction

Bioactivity
Description
Dalbavancin (BI-397), a novel second-generation lipoglycopeptide antibiotic, possesses in vitro activity against a variety of Gram-positive pathogens including methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE),Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively
Targets&IC50
S. aureus:0.06 μg/mL (MIC90), Bacillus anthracis:0.25 μg/mL (MIC90)
SynonymsVER-001, VER 001, BI-397, BI397, BI 397, A-A-1 antibiotic
Chemical Properties
Molecular Weight1816.71
FormulaC88H100Cl2N10O28
Cas No.171500-79-1
Smiles[H][C@@]1(Oc2c3Oc4ccc(C[C@@]5([H])NC(=O)[C@H](NC)c6ccc(O)c(Oc7cc(O)c(Cl)c(c7)[C@]([H])(NC5=O)C(=O)N[C@]5([H])c(c3)cc2Oc2ccc(cc2Cl)[C@@H](O)[C@]2([H])NC(=O)[C@]([H])(NC5=O)c3ccc(O)c(c3)-c3c(O[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)cc(O)cc3[C@H](NC2=O)C(=O)NCCCN(C)C)c6)cc4)O[C@@H]([C@@H](O)[C@H](O)[C@H]1NC(=O)CCCCCCCCC(C)C)C(O)=O
Relative Density.1.59 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (53.96 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.5504 mL2.7522 mL5.5045 mL27.5223 mL
5 mM0.1101 mL0.5504 mL1.1009 mL5.5045 mL
10 mM0.0550 mL0.2752 mL0.5504 mL2.7522 mL
20 mM0.0275 mL0.1376 mL0.2752 mL1.3761 mL
50 mM0.0110 mL0.0550 mL0.1101 mL0.5504 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

VER001semisyntheticMRSAMDL-63397MDL63397MDL 63397lipoglycopeptideGram-positiveDalbavancincSSSIsBacterialBacillusantibioticanthracisA-A 1
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