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Dalbavancin

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Catalog No. T21358Cas No. 171500-79-1
Alias VER-001, VER 001, BI-397, BI397, BI 397, A-A-1 antibiotic

Dalbavancin (BI-397), a novel second-generation lipoglycopeptide antibiotic, possesses in vitro activity against a variety of Gram-positive pathogens including methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE),Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively

Dalbavancin

Dalbavancin

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🥰Excellent
Purity: 99.09%
Catalog No. T21358Alias VER-001, VER 001, BI-397, BI397, BI 397, A-A-1 antibioticCas No. 171500-79-1
Dalbavancin (BI-397), a novel second-generation lipoglycopeptide antibiotic, possesses in vitro activity against a variety of Gram-positive pathogens including methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE),Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$52In Stock-
5 mg$123In Stock-
10 mg$195In Stock-
25 mg$393In Stock-
50 mg$591In Stock-
1 mL x 10 mM (in DMSO)$205In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.09%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Dalbavancin (BI-397), a novel second-generation lipoglycopeptide antibiotic, possesses in vitro activity against a variety of Gram-positive pathogens including methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE),Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively
Targets&IC50
Bacillus anthracis:0.25 μg/mL (MIC90), S. aureus:0.06 μg/mL (MIC90)
SynonymsVER-001, VER 001, BI-397, BI397, BI 397, A-A-1 antibiotic
Chemical Properties
Molecular Weight1816.71
FormulaC88H100Cl2N10O28
Cas No.171500-79-1
Smiles[H][C@@]1(Oc2c3Oc4ccc(C[C@@]5([H])NC(=O)[C@H](NC)c6ccc(O)c(Oc7cc(O)c(Cl)c(c7)[C@]([H])(NC5=O)C(=O)N[C@]5([H])c(c3)cc2Oc2ccc(cc2Cl)[C@@H](O)[C@]2([H])NC(=O)[C@]([H])(NC5=O)c3ccc(O)c(c3)-c3c(O[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)cc(O)cc3[C@H](NC2=O)C(=O)NCCCN(C)C)c6)cc4)O[C@@H]([C@@H](O)[C@H](O)[C@H]1NC(=O)CCCCCCCCC(C)C)C(O)=O
Relative Density.1.59 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (55.04 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.5504 mL2.7522 mL5.5045 mL27.5223 mL
5 mM0.1101 mL0.5504 mL1.1009 mL5.5045 mL
10 mM0.0550 mL0.2752 mL0.5504 mL2.7522 mL
20 mM0.0275 mL0.1376 mL0.2752 mL1.3761 mL
50 mM0.0110 mL0.0550 mL0.1101 mL0.5504 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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