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Sodium Iodoacetate

Name: Sodium Iodoacetate
Brand: TargetMol
SKU: T87414
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T87414Cas No. 305-53-3

Alias Iodoacetic Acid Sodium Salt

Sodium Iodoacetate is a specific and irreversible inhibitor of GAPDH that suppresses glycolysis. It is commonly employed to establish osteoarthritis models.

Sodium Iodoacetate

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Purity: 97.07%

Catalog No. T87414Alias Iodoacetic Acid Sodium SaltCas No. 305-53-3

Sodium Iodoacetate is a specific and irreversible inhibitor of GAPDH that suppresses glycolysis. It is commonly employed to establish osteoarthritis models.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock
5 g	$48	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:97.07%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Sodium Iodoacetate is a specific and irreversible inhibitor of GAPDH that suppresses glycolysis. It is commonly employed to establish osteoarthritis models.
In vivo	A single injection of Sodium Iodoacetate (0, 0.3, and 3 mg/joint) into the right knee joint space induced synovial cell proliferation and moderate fibrotic changes in Wistar rats, accompanied by mild inflammatory cell infiltration [3].
Synonyms	Iodoacetic Acid Sodium Salt

Chemical Properties

Molecular Weight	207.93
Formula	C₂H₂INaO₂
Cas No.	305-53-3
Smiles	O=C(CI)[O-].[Na+]
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 80 mg/mL (384.74 mM), Sonication is recommended.

H2O: ≥ 80 mg/mL, Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.8093 mL	24.0466 mL	48.0931 mL	240.4655 mL
5 mM	0.9619 mL	4.8093 mL	9.6186 mL	48.0931 mL
10 mM	0.4809 mL	2.4047 mL	4.8093 mL	24.0466 mL
20 mM	0.2405 mL	1.2023 mL	2.4047 mL	12.0233 mL
50 mM	0.0962 mL	0.4809 mL	0.9619 mL	4.8093 mL
100 mM	0.0481 mL	0.2405 mL	0.4809 mL	2.4047 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc