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Efmitermant alfa
(Synonyms: ACE083) Copy Product Info
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Synonyms: ACE083
Catalog No. T82500 Copy Product Info
🥰Excellent
Efmitermant alfa (ACE-083), a follistatin-based fusion protein with localized action, functions as a muscle-promoting agent and is utilized in the study of muscle disorders [1] [2].
Efmitermant alfa
Cas No. 1644543-31-6
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Efmitermant alfa (ACE-083), a follistatin-based fusion protein with localized action, functions as a muscle-promoting agent and is utilized in the study of muscle disorders [1] [2]. |
| In vitro | ACE-083 (0-60 nM) exhibits high affinity for heparin and the extracellular matrix [1]. |
| In vivo | ACE-083 (muscle injection; 0-100 µg; biweekly for 4 weeks) induced local, dose-dependent hypertrophy in the injected muscles of both wild-type mice and mouse models of Charcot-Marie-Tooth disease (CMT) and Duchenne muscular dystrophy [1]. Moreover, the compound enhanced in situ isometric contraction force in the tibialis anterior muscle of treated wild-type and disease model mice, and increased dorsiflexion torque at the ankle joint in CMT mice [1]. |
| Synonyms | ACE083 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | MSTN |
| Cas No. | 1644543-31-6 |
| Storage | -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Efmitermant alfa in vivo | Efmitermant alfa in vitro
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