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Triacetylresveratrol

Name: Triacetylresveratrol
Brand: TargetMol
SKU: T5668
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5668Cas No. 42206-94-0

Alias Acetyl-trans-resveratrol

Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity,it inhibits the phosphorylation of STAT3 and NFκB, down-regulates Mcl-1, and up-regulates Bim and Puma in pancreatic cancer cells.

Triacetylresveratrol

🥰Excellent

Purity: 99.81%

Catalog No. T5668Alias Acetyl-trans-resveratrolCas No. 42206-94-0

Pack Size	Price	Availability
200 mg	$40	In Stock
500 mg	$68	In Stock
1 g	$100	In Stock
2 g	$145	In Stock

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Purity:99.81%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity,it inhibits the phosphorylation of STAT3 and NFκB, down-regulates Mcl-1, and up-regulates Bim and Puma in pancreatic cancer cells.
In vitro	Acetyl-trans-resveratrol inhibited cell viability, and induced apoptosis of pancreatic cancer cells in a concentration and incubation time-dependent manner[1].
In vivo	Acetyl-trans-resveratrol significantly inhibited intracranial tumor growth and prolonged survival in these mouse models[2].
Cell Research	Apoptosis was determined by using apoptosis detection kit according to the manufacturers instructions.?Briefly, cells were treated with the indicated dosage of Acetyl-trans-resveratrol?for 48 h. The untreated and?treated cells were washed with PBS buffer and gently suspended in Annexin V binding buffer and incubated with Annexin V-FITC (20 μg/mL) and PI (20 μg/mL) for 15 minutes in the dark.?Flow cytometry analysis was performed using Cellquest software.
Synonyms	Acetyl-trans-resveratrol

Chemical Properties

Molecular Weight	354.35
Formula	C₂₀H₁₈O₆
Cas No.	42206-94-0
Smiles	CC(=O)Oc1ccc(\C=C\c2cc(OC(C)=O)cc(OC(C)=O)c2)cc1
Relative Density.	1.241 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (141.1 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8221 mL	14.1103 mL	28.2207 mL	141.1034 mL
5 mM	0.5644 mL	2.8221 mL	5.6441 mL	28.2207 mL
10 mM	0.2822 mL	1.4110 mL	2.8221 mL	14.1103 mL
20 mM	0.1411 mL	0.7055 mL	1.4110 mL	7.0552 mL
50 mM	0.0564 mL	0.2822 mL	0.5644 mL	2.8221 mL
100 mM	0.0282 mL	0.1411 mL	0.2822 mL	1.4110 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc