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Morin monohydrate

Name: Morin monohydrate
Brand: TargetMol
SKU: T6596
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

😃Good

Catalog No. T6596Cas No. 6202-27-3

Alias oxylon pomiferum monohydrate, Calico Yellow monohydrate, Aurantica monohydrate, Al-Morin monohydrate

Morin monohydrate (oxylon pomiferum monohydrate) is a flavonoid extracted from Morus alba plant with anticancer, antioxidant, and anti-inflammatory activities, which reduces T-2 toxin-induced TNF-alpha, COX-2, IL-1β, IL-6, caspase-1, caspase-3, and caspase-11 mRNA. BML-286 is a WNP-containing WNP-containing BML-286, which reduces T-2 toxin-induced TNF-α, COX-2, IL-1β, IL-6, caspase-1, caspase-3, and caspase-11 mRNA expression, and ameliorates T-2 toxin-induced injury by decreasing malondialdehyde (MDA) and increasing superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), and glutathione peroxidase (GSH-PX).

Morin monohydrate

😃Good

Purity: 97.06%

Catalog No. T6596Alias oxylon pomiferum monohydrate, Calico Yellow monohydrate, Aurantica monohydrate, Al-Morin monohydrateCas No. 6202-27-3

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$38	In Stock	In Stock
10 mg	$52	In Stock	In Stock
25 mg	$82	In Stock	In Stock
50 mg	$117	In Stock	In Stock
100 mg	$189	In Stock	In Stock
200 mg	$309	-	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:97.06%

Appearance:Solid

Color:Yellow

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Morin monohydrate (oxylon pomiferum monohydrate) is a flavonoid extracted from Morus alba plant with anticancer, antioxidant, and anti-inflammatory activities, which reduces T-2 toxin-induced TNF-alpha, COX-2, IL-1β, IL-6, caspase-1, caspase-3, and caspase-11 mRNA. BML-286 is a WNP-containing WNP-containing BML-286, which reduces T-2 toxin-induced TNF-α, COX-2, IL-1β, IL-6, caspase-1, caspase-3, and caspase-11 mRNA expression, and ameliorates T-2 toxin-induced injury by decreasing malondialdehyde (MDA) and increasing superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), and glutathione peroxidase (GSH-PX).
In vitro	Morin hydrate(Aurantica) is a flavonoid isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava). Morin hydrate as an antioxidant improves the survival time of rat glomerular mesangial cells which are attacked by oxyradicals. [1] Morin is also an effective hepatoprotector, both in cultured cells and in hepatic ischemia-reperfusion. [2] Morin hydrate is a new type of Islet Amyloid Polypeptide (IAPP) inhibitor, which may be used in type-2 diabetes and islet cell transplants. [3]
Synonyms	oxylon pomiferum monohydrate, Calico Yellow monohydrate, Aurantica monohydrate, Al-Morin monohydrate

Chemical Properties

Molecular Weight	320.25
Formula	C₁₅H₁₂O₈
Cas No.	6202-27-3
Smiles	O=C1C(O)=C(OC=2C=C(O)C=C(O)C12)C=3C=CC(O)=CC3O.O
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: <1 mg/mL

Ethanol: 2 mg/mL (6.25 mM), Heating is recommended.

DMSO: 120 mg/mL (374.71 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1226 mL	15.6128 mL	31.2256 mL	156.1280 mL
5 mM	0.6245 mL	3.1226 mL	6.2451 mL	31.2256 mL

DMSO

	1mg	5mg	10mg	50mg
10 mM	0.3123 mL	1.5613 mL	3.1226 mL	15.6128 mL
20 mM	0.1561 mL	0.7806 mL	1.5613 mL	7.8064 mL
50 mM	0.0625 mL	0.3123 mL	0.6245 mL	3.1226 mL
100 mM	0.0312 mL	0.1561 mL	0.3123 mL	1.5613 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc