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Anti-BMI-1 Antibody (3J519)

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Catalog No. TMAH-00116 Copy Product Info
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Anti-BMI-1 Antibody (3J519) is an antibody targeting BMI-1. Anti-BMI-1 Antibody (3J519) can be used in ELISA,IHC,WB.
Anti-BMI-1 Antibody
(3J519)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2087-10 days7-10 days
100 μL$3487-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-BMI-1 Antibody (3J519) is an antibody targeting BMI-1. Anti-BMI-1 Antibody (3J519) can be used in ELISA,IHC,WB.
Ig Type
Rabbit IgG
Clone
3J519
Reactivity
Human
Application
Recommended Dose
WB:1:500-1:5000; IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationNucleus. Cytoplasm.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundComponent of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human Bmi1
Antigen Species
Human
Gene Name
BMI1
Gene ID
Uniprot ID
Biology Area
Epigenetics and Nuclear Signaling, Cancer, Cell biology, Stem cells
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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