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Metallo β-lactamase ligand 1

Name: Metallo β-lactamase ligand 1
Brand: TargetMol
SKU: T38476
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T38476Cas No. 1087784-71-1

Metallo β-lactamase ligand 1 is an inhibitor of class B β-lactamase exhibiting antibacterial activities.

Metallo β-lactamase ligand 1

🥰Excellent

Purity: 98.17%

Catalog No. T38476Cas No. 1087784-71-1

Metallo β-lactamase ligand 1 is an inhibitor of class B β-lactamase exhibiting antibacterial activities.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$48	-	In Stock
50 mg	$68	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:98.17%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Metallo β-lactamase ligand 1 is an inhibitor of class B β-lactamase exhibiting antibacterial activities.
In vitro	The toxicity of Metallo β-lactamase ligand 1 is extremely low in HeLa cells[1].
In vivo	Administration of Metallo β-lactamase ligand 1 significantly improves the survival rate in mice infected with an experimental strain (E. coli strain into which a plasmid encoding class B β-lactamase (IMP-1) is introduced)[1].

Chemical Properties

Molecular Weight	219.22
Formula	C₇H₉NO₅S
Cas No.	1087784-71-1
Smiles	S(N)(=O)(=O)C=1C(C(O)=O)=C(C)OC1C
Relative Density.	1.498 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (250.89 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.5616 mL	22.8081 mL	45.6163 mL	228.0814 mL
5 mM	0.9123 mL	4.5616 mL	9.1233 mL	45.6163 mL
10 mM	0.4562 mL	2.2808 mL	4.5616 mL	22.8081 mL
20 mM	0.2281 mL	1.1404 mL	2.2808 mL	11.4041 mL
50 mM	0.0912 mL	0.4562 mL	0.9123 mL	4.5616 mL
100 mM	0.0456 mL	0.2281 mL	0.4562 mL	2.2808 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc