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Fosfructose, sodium salt, hydrate (1:3:8)

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Catalog No. T37984Cas No. 81028-91-3
Alias D-Fructose-1,6-bisphosphate , sodium salt, hydrate (1:3:8)

D-Fructose-1,6-bisphosphate sodium salt hydrate is the intermediate in carbohydrate metabolism, including glycolysis and gluconeogenesis. During glycolysis, it is produced by phosphorylation of fructose-6-phosphate by phosphofructokinase. The reverse reaction mediated by fructose-1, 6-diphosphatase-1 is one of the rate-limiting steps of gluconeogenesis. The same reaction occurs in the chloroplasts of plants, D-Fructose-1,6-bisphosphate sodium salt hydrate as part of the reducing pentose phosphate cycle. Since cancer cells use glycolysis as a primary source of metabolic energy production, this pathway has become a major target for cancer chemotherapy.

Fosfructose, sodium salt, hydrate (1:3:8)
Other Forms of Fosfructose, sodium salt, hydrate (1:3:8):

Fosfructose, sodium salt, hydrate (1:3:8)

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Catalog No. T37984Alias D-Fructose-1,6-bisphosphate , sodium salt, hydrate (1:3:8)Cas No. 81028-91-3
D-Fructose-1,6-bisphosphate sodium salt hydrate is the intermediate in carbohydrate metabolism, including glycolysis and gluconeogenesis. During glycolysis, it is produced by phosphorylation of fructose-6-phosphate by phosphofructokinase. The reverse reaction mediated by fructose-1, 6-diphosphatase-1 is one of the rate-limiting steps of gluconeogenesis. The same reaction occurs in the chloroplasts of plants, D-Fructose-1,6-bisphosphate sodium salt hydrate as part of the reducing pentose phosphate cycle. Since cancer cells use glycolysis as a primary source of metabolic energy production, this pathway has become a major target for cancer chemotherapy.
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1 g$29In StockIn Stock
5 g$53-In Stock
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Purity:＞99.99%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
D-Fructose-1,6-bisphosphate sodium salt hydrate is the intermediate in carbohydrate metabolism, including glycolysis and gluconeogenesis. During glycolysis, it is produced by phosphorylation of fructose-6-phosphate by phosphofructokinase. The reverse reaction mediated by fructose-1, 6-diphosphatase-1 is one of the rate-limiting steps of gluconeogenesis. The same reaction occurs in the chloroplasts of plants, D-Fructose-1,6-bisphosphate sodium salt hydrate as part of the reducing pentose phosphate cycle. Since cancer cells use glycolysis as a primary source of metabolic energy production, this pathway has become a major target for cancer chemotherapy.
SynonymsD-Fructose-1,6-bisphosphate , sodium salt, hydrate (1:3:8)
Chemical Properties
Molecular Weight550.18
FormulaC6H27Na3O20P2
Cas No.81028-91-3
SmilesC([C@H]([C@H]([C@@H](C(=O)COP(=O)(O)[O-])O)O)O)OP(=O)([O-])[O-].O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+]
Storage & Solubility Information
Storagestore at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: < 1 mg/mL (insoluble or slightly soluble)
PBS (pH 7.2): 10 mg/mL (18.18 mM), Sonication is recommended.
H2O: 115 mg/mL (209.02 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/H2O
1mg5mg10mg50mg
1 mM1.8176 mL9.0879 mL18.1759 mL90.8793 mL
5 mM0.3635 mL1.8176 mL3.6352 mL18.1759 mL
10 mM0.1818 mL0.9088 mL1.8176 mL9.0879 mL
H2O
1mg5mg10mg50mg
20 mM0.0909 mL0.4544 mL0.9088 mL4.5440 mL
50 mM0.0364 mL0.1818 mL0.3635 mL1.8176 mL
100 mM0.0182 mL0.0909 mL0.1818 mL0.9088 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

D-Fructose-1,6-bisphosphate sodium HydrateDFructose1,6bisphosphate (sodium salt hydrate)D Fructose 1,6 bisphosphate (sodium salt hydrate)
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