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Anti-IL-37 Antibody (9W745) is a Mouse antibody targeting IL-37. Anti-IL-37 Antibody (9W745) can be used in ELISA,ELISA(Cap).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $69 | 7-10 days | |
100 μL | $198 | 7-10 days |
Description | Anti-IL-37 Antibody (9W745) is a Mouse antibody targeting IL-37. Anti-IL-37 Antibody (9W745) can be used in ELISA,ELISA(Cap). |
Alias | interleukin 37, IL-37, IL37, IL-1RP1, IL1RP1, IL-1H4, IL1H4, IL-1H, IL-1F7, IL1F7, FIL1Z, FIL1(ζ), FIL1(ZETA), FIL1 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 9W745 |
Reactivity | Human |
Application | ELISA,ELISA(Cap) |
Recommended Dose | ELISA: 1:1000-1:2000; ELISA(Cap): 1:250-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL37 / IL1F7 / IL-1H4 (rh IL37 / IL1F7 / IL-1H4; TMPY-02597; Q9NZH6-2; Lys27-Asp192). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the expression of IL-1F7b protein in discrete cell populations including plasma cells and tumor cells. These data suggest that IL-1F7 may be involved in immune response, inflammatory diseases, and/or cancer. Through constructing an adenoviral vector that allows high-level expression in murine and human cells, it has been demonstrated that the ability of adenovirus-mediated gene transfer of IL1F7 to induce an IL-12- and Fas ligand-dependent anti-tumor response. Complete inhibition of tumor growth was observed following multiple injections of IL1F7 in most animals. These results suggest that IL1F7 could play a role in both innate and adaptive immune responses, similar to IL-18. Moreover, IL1F7 could be useful for cancer gene therapy. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human IL37 / IL1F7 / IL-1H4 Protein (TMPY-02597) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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