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(-)-3,5-Dicaffeoylquinic acid

🥰Excellent
Catalog No. TL0005Cas No. 89919-62-0
Alias Isochlorogenic Acid A, 3,5-Dicaffeoylquinic Acid, (-)-3,5-Dicaffeoyl quinic acid

3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) is an isolated compound from Artemisia argyi; its ester derivatives exert anti-leucyl-tRNA synthetase of Giardia lamblia (GlLeuRS) and potential anti-giardial effects. 3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) as a neuraminidase inhibitory ligand in Flos Lonicerae, it has neuroprotective effects on SH-SY5Y cells and senescence-accelerated-prone mice 8 through the up-regulation of phosphoglycerate kinase-1. 3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) also has antioxidant and anti-complementary activities.

(-)-3,5-Dicaffeoylquinic acid
Other Forms of (-)-3,5-Dicaffeoylquinic acid:
Isochlorogenic acid AT50982450-53-5
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(-)-3,5-Dicaffeoylquinic acid

🥰Excellent
Purity: 99.72%
Catalog No. TL0005Alias Isochlorogenic Acid A, 3,5-Dicaffeoylquinic Acid, (-)-3,5-Dicaffeoyl quinic acidCas No. 89919-62-0
3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) is an isolated compound from Artemisia argyi; its ester derivatives exert anti-leucyl-tRNA synthetase of Giardia lamblia (GlLeuRS) and potential anti-giardial effects. 3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) as a neuraminidase inhibitory ligand in Flos Lonicerae, it has neuroprotective effects on SH-SY5Y cells and senescence-accelerated-prone mice 8 through the up-regulation of phosphoglycerate kinase-1. 3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) also has antioxidant and anti-complementary activities.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$61In StockIn Stock
5 mg$142In StockIn Stock
10 mg$198In StockIn Stock
25 mg$358In StockIn Stock
50 mg$558In StockIn Stock
100 mg$785-In Stock
1 mL x 10 mM (in DMSO)$187In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.72%
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Product Introduction

Bioactivity
Description
3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) is an isolated compound from Artemisia argyi; its ester derivatives exert anti-leucyl-tRNA synthetase of Giardia lamblia (GlLeuRS) and potential anti-giardial effects. 3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) as a neuraminidase inhibitory ligand in Flos Lonicerae, it has neuroprotective effects on SH-SY5Y cells and senescence-accelerated-prone mice 8 through the up-regulation of phosphoglycerate kinase-1. 3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) also has antioxidant and anti-complementary activities.
SynonymsIsochlorogenic Acid A, 3,5-Dicaffeoylquinic Acid, (-)-3,5-Dicaffeoyl quinic acid
Chemical Properties
Molecular Weight516.45
FormulaC25H24O12
Cas No.89919-62-0
SmilesO(C(/C=C/C1=CC(O)=C(O)C=C1)=O)[C@H]2[C@@H](O)[C@H](OC(/C=C/C3=CC(O)=C(O)C=C3)=O)C[C@@](C(O)=O)(O)C2
Relative Density.1.64
ColorBlack
Appearancesolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mg/mL (19.36 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (1.94 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9363 mL9.6815 mL19.3630 mL96.8148 mL
5 mM0.3873 mL1.9363 mL3.8726 mL19.3630 mL
10 mM0.1936 mL0.9681 mL1.9363 mL9.6815 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

tRNA synthetase of Giardia lambliaInhibitorinhibit3,5-O-Dicaffeoylquinic acid3,5ODicaffeoylquinic acid3,5-Dicaffeoyl quinic acid3,5 O Dicaffeoylquinic acid
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