Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BRF110 is a brain penetrant, potent and selective agonist of nuclear receptor-related 1 (Nurr1):Retinoid X receptor α (RXRα) heterodimer. BRF110 is a neuroprotective agent that prevents dopaminergic neuron demise and striatal dopaminergic denervation in vivo against PD-causing toxins. It induced dopamine biosynthesis in vivo. BRF110 chronic dosing does not induce dyskinesia in mice model.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | BRF110 is a brain penetrant, potent and selective agonist of nuclear receptor-related 1 (Nurr1):Retinoid X receptor α (RXRα) heterodimer. BRF110 is a neuroprotective agent that prevents dopaminergic neuron demise and striatal dopaminergic denervation in vivo against PD-causing toxins. It induced dopamine biosynthesis in vivo. BRF110 chronic dosing does not induce dyskinesia in mice model. |
Molecular Weight | 413.39 |
Formula | C22H18F3N3O2 |
CAS No. | 2095489-35-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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BRF110 2095489-35-1 MK 8931 SCH900931 BRF 110 MK-8931-009 MK8931 BRF-110 Verubecestat TFA SCH-900931 SCH 900931 inhibitor inhibit