Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-Aminoacylase 1 Antibody (1H430)
😃Good
Catalog No. TMAY-00963
Alias HEL-S-5, aminoacylase 1, ACY1D, ACY-1
Anti-Aminoacylase 1 Antibody (1H430) is a Rabbit antibody targeting Aminoacylase 1. Anti-Aminoacylase 1 Antibody (1H430) can be used in FCM,ICC/IF.
Anti-Aminoacylase 1 Antibody (1H430)
Anti-Aminoacylase 1 Antibody (1H430)
😃Good
Catalog No. TMAY-00963Alias HEL-S-5, aminoacylase 1, ACY1D, ACY-1
Anti-Aminoacylase 1 Antibody (1H430) is a Rabbit antibody targeting Aminoacylase 1. Anti-Aminoacylase 1 Antibody (1H430) can be used in FCM,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Aminoacylase 1 Antibody (1H430) is a Rabbit antibody targeting Aminoacylase 1. Anti-Aminoacylase 1 Antibody (1H430) can be used in FCM,ICC/IF. |
| Alias | HEL-S-5, aminoacylase 1, ACY1D, ACY-1 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 1H430 |
| Reactivity | Human |
| Verified Activity | 1. Immunofluorescence staining of Human ACY1 in Hela or SKBR3 cells. Cells were fixed with 4% PFA, permeabilzed with 1% Triton X-100 in PBS, blocked with 10% serum, and incubated with Rabbit anti-Human ACY1 monoclonal antibody (1:60). Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (left panel, captured by laser confocal scanning microscope; right panel, captured by fluorescence microscope), countstained with DAPI (blue). Positive staining was localized to cytoplasm. 2. Flow cytometric analysis of Human ACY1 expression on HepG2 cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human ACY1, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM,ICC/IF |
| Recommended Dose | ICC-IF: 1:20-1:100; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ACY1 / Aminoacylase-1 (rh ACY1 / Aminoacylase-1; TMPY-01058; NP_000657.1; Met1-Ser408). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Aminoacylase 1 (ACY1), a metalloenzyme that removes amide-linked ACY1 groups from amino acids and may play a role in regulating responses to oxidative stress. Both the C-terminal fragment found in the two-hybrid screen and full-length ACY1 co-immunoprecipitate with SphK1. Though both C-terminal and full-length proteins slightly reduce SphK1 activity measured in vitro, the C-terminal fragment inhibits while full-length ACY1 potentiates the effects of SphK1 on proliferation and apoptosis. It suggested that ACY1 physically interacts with SphK1 and may influence its physiological functions. As a homodimeric zinc-binding enzyme, Aminoacylase 1 catalyzes the hydrolysis of N alpha-acylated amino acids. Deficiency of Aminoacylase 1 due to mutations in the Aminoacylase 1 (ACY1) gene follows an autosomal-recessive trait of inheritance and is characterized by accumulation of N-acetyl amino acids in the urine. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human ACY1 / Aminoacylase-1 protein (TMPY-01058) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-Aminoacylase 1 Antibody (1H430) | purchase Anti-Aminoacylase 1 Antibody (1H430) | Anti-Aminoacylase 1 Antibody (1H430) cost | order Anti-Aminoacylase 1 Antibody (1H430)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.