Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM. FSEN1 induces iron death in cancer cells by inhibiting FSP1. FSEN1 can be used to prevent and treat cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 139.00 | |
5 mg | In stock | $ 297.00 | |
10 mg | In stock | $ 455.00 | |
25 mg | In stock | $ 736.00 | |
50 mg | In stock | $ 987.00 | |
100 mg | In stock | $ 1,360.00 |
Description | FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM. FSEN1 induces iron death in cancer cells by inhibiting FSP1. FSEN1 can be used to prevent and treat cancer. |
In vitro | FSEN1 (0-15 µM; H460C Cas9 cells) exhibits a synthetic lethality effect with GPX4 inhibitors and sensitizes cancer cells to ferroptosis by inhibiting FSP1[1]. |
Synonyms | 3-(4-bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazole |
Molecular Weight | 484.41 |
Formula | C22H22BrN5OS |
CAS No. | 862808-01-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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FSEN1 862808-01-3 Apoptosis Ferroptosis FSEN-1 3-(4-bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazole FSEN 1 inhibitor inhibit