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D13

Name: D13
Brand: TargetMol
SKU: T36054
Rating: 4.5 (1 reviews)

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Catalog No. T36054Cas No. 321945-27-1

D13 is an acylhydrazone antifungal.1 It is active against C. neoformans in vitro (MIC80 = 0.06 μg/ml). D13 (20 mg/kg per day, p.o.) increases survival in mouse models of C. neoformans, C. albicans, or A. fumigatus infection.

D13

😃Good

Catalog No. T36054Cas No. 321945-27-1

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$133	35 days	35 days
5 mg	$420	35 days	35 days
10 mg	$772	35 days	35 days
25 mg	$1,750	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	476.95
Formula	C₁₄H₉Br₃N₂O₂
Cas No.	321945-27-1
Smiles	C(=NNC(=O)C1=CC=C(Br)C=C1)C2=C(O)C(Br)=CC(Br)=C2
Relative Density.	1.96 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mg/mL (20.97 mM), Sonication is recommended.

DMF: 30 mg/mL (62.9 mM), Sonication is recommended.

Solution Preparation Table

DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	2.0967 mL	10.4833 mL	20.9666 mL	104.8328 mL
5 mM	0.4193 mL	2.0967 mL	4.1933 mL	20.9666 mL
10 mM	0.2097 mL	1.0483 mL	2.0967 mL	10.4833 mL
20 mM	0.1048 mL	0.5242 mL	1.0483 mL	5.2416 mL

DMF

	1mg	5mg	10mg	50mg
50 mM	0.0419 mL	0.2097 mL	0.4193 mL	2.0967 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

D-13D13D 13

D13

D13

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