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D13

Name: D13
Brand: TargetMol
SKU: T36054
Rating: 4.5 (1 reviews)

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Catalog No. T36054Cas No. 321945-27-1

D13 is an acylhydrazone antifungal.1 It is active against C. neoformans in vitro (MIC80 = 0.06 μg/ml). D13 (20 mg/kg per day, p.o.) increases survival in mouse models of C. neoformans, C. albicans, or A. fumigatus infection.

D13

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Catalog No. T36054Cas No. 321945-27-1

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$133	35 days	35 days
5 mg	$420	35 days	35 days
10 mg	$772	35 days	35 days
25 mg	$1,750	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	476.95
Formula	C₁₄H₉Br₃N₂O₂
Cas No.	321945-27-1
Smiles	C(=NNC(=O)C1=CC=C(Br)C=C1)C2=C(O)C(Br)=CC(Br)=C2
Relative Density.	1.96 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mg/mL (20.97 mM), Sonication is recommended.

DMF: 30 mg/mL (62.9 mM), Sonication is recommended.

Solution Preparation Table

DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	2.0967 mL	10.4833 mL	20.9666 mL	104.8328 mL
5 mM	0.4193 mL	2.0967 mL	4.1933 mL	20.9666 mL
10 mM	0.2097 mL	1.0483 mL	2.0967 mL	10.4833 mL
20 mM	0.1048 mL	0.5242 mL	1.0483 mL	5.2416 mL

DMF

	1mg	5mg	10mg	50mg
50 mM	0.0419 mL	0.2097 mL	0.4193 mL	2.0967 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

D-13D13D 13

D13

D13

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