Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GEM-5, a gemcitabine-based conjugate incorporating a HIF-1α inhibitor (YC-1) (IC 50 =30 nM), notably suppresses HIF-1α expression while enhancing tumor suppressor p53 expression. It induces apoptosis in A2780 cells and curbs tumor growth [1].
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Description | GEM-5, a gemcitabine-based conjugate incorporating a HIF-1α inhibitor (YC-1) (IC 50 =30 nM), notably suppresses HIF-1α expression while enhancing tumor suppressor p53 expression. It induces apoptosis in A2780 cells and curbs tumor growth [1]. |
Molecular Weight | 649.6 |
Formula | C32H29F2N5O8 |
CAS No. | 2233543-49-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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GEM-5 2233543-49-0 inhibitor inhibit