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Tositumomab (Synonyms: V10XA53, Anti-Human CD20 Recombinant Antibody)

Catalog No. T76835 Copy Product Info
Purity: 95%
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Tositumomab is a murine IgG2a lambda monoclonal antibody that selectively binds to the CD20 antigen expressed on the surface of normal and malignant B lymphocytes. Tositumomab is widely utilized in research for B cell-targeted therapies, immunological studies, and the development of radioimmunoconjugates for cancer treatment.

Tositumomab

Copy Product Info
🥰Excellent
Catalog No. T76835
Synonyms V10XA53, Anti-Human CD20 Recombinant Antibody

Tositumomab is a murine IgG2a lambda monoclonal antibody that selectively binds to the CD20 antigen expressed on the surface of normal and malignant B lymphocytes. Tositumomab is widely utilized in research for B cell-targeted therapies, immunological studies, and the development of radioimmunoconjugates for cancer treatment.

Tositumomab
Cas No. 192391-48-3
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$247-In Stock
5 mg$645-In Stock
10 mg$987-In Stock
25 mg$1,460-In Stock
50 mg$1,970-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:95.1% (SDS-PAGE); 97.5% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Tositumomab is a murine IgG2a lambda monoclonal antibody that selectively binds to the CD20 antigen expressed on the surface of normal and malignant B lymphocytes. Tositumomab is widely utilized in research for B cell-targeted therapies, immunological studies, and the development of radioimmunoconjugates for cancer treatment.
In vitro
In the mouse xenograft model of human Raji lymphoma cells, Tositumomab (131I-tositumomab) at a dose of 2,035 kBq could inhibit tumor growth and prolong the survival period [1].
In vivo
In the mouse xenograft model of human Raji lymphoma cells, Tositumomab (131I-tositumomab) at a dose of 2,035 kBq could inhibit tumor growth and prolong the survival period [1].
SynonymsV10XA53, Anti-Human CD20 Recombinant Antibody
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCD20
Chemical Properties
Molecular Weight147.25 kDa
Cas No.192391-48-3
Antibody Information
IsotypemIgG2a
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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