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Tositumomab
🥰Excellent
Catalog No. T76835Cas No. 192391-48-3
Alias V10XA53, Anti-Human CD20 Recombinant Antibody
Tositumomab is a murine IgG2a lambda monoclonal antibody that selectively binds to the CD20 antigen expressed on the surface of normal and malignant B lymphocytes. Tositumomab is widely utilized in research for B cell-targeted therapies, immunological studies, and the development of radioimmunoconjugates for cancer treatment.
Tositumomab
Tositumomab
🥰Excellent
Purity: 95%
Catalog No. T76835Alias V10XA53, Anti-Human CD20 Recombinant AntibodyCas No. 192391-48-3
Tositumomab is a murine IgG2a lambda monoclonal antibody that selectively binds to the CD20 antigen expressed on the surface of normal and malignant B lymphocytes. Tositumomab is widely utilized in research for B cell-targeted therapies, immunological studies, and the development of radioimmunoconjugates for cancer treatment.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | - | In Stock | |
| 5 mg | $645 | - | In Stock | |
| 10 mg | $987 | - | In Stock | |
| 25 mg | $1,460 | - | In Stock | |
| 50 mg | $1,970 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Tositumomab is a murine IgG2a lambda monoclonal antibody that selectively binds to the CD20 antigen expressed on the surface of normal and malignant B lymphocytes. Tositumomab is widely utilized in research for B cell-targeted therapies, immunological studies, and the development of radioimmunoconjugates for cancer treatment. |
| In vitro | In the mouse xenograft model of human Raji lymphoma cells, Tositumomab (131I-tositumomab) at a dose of 2,035 kBq could inhibit tumor growth and prolong the survival period [1]. |
| In vivo | In the mouse xenograft model of human Raji lymphoma cells, Tositumomab (131I-tositumomab) at a dose of 2,035 kBq could inhibit tumor growth and prolong the survival period [1]. |
| Synonyms | V10XA53, Anti-Human CD20 Recombinant Antibody |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Host Species | ＜ 1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID |
| Molecular Weight | 143.86 (kDa) |
| Cas No. | 192391-48-3 |
| Color | Transparent |
| Appearance | Liquid |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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