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6-Hydroxy Chlorzoxazone

Name: 6-Hydroxy Chlorzoxazone
Brand: TargetMol
SKU: T37306
Price: 89 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T37306 Copy Product Info

Purity: 99.62%

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6-Hydroxy Chlorzoxazone is the major metabolite of the muscle relaxant chlorzoxazone. 6-Hydroxy Chlorzoxazone is a chlorinated benzoxazolone generated by metabolism via the CYP2E1 enzyme in the liver. 6-Hydroxy Chlorzoxazone serves as a reliable marker for assessing CYP2E1 metabolic activity and is used as a reference standard in biochemical research.

Cas No. 1750-45-4

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Pack Size	Price	USA Stock	Global Stock
1 mg	$89	-	In Stock
5 mg	$197	-	In Stock
10 mg	$322	-	In Stock
25 mg	$538	-	In Stock
50 mg	$768	-	In Stock
1 mL x 10 mM (in DMSO)	$193	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.62%

Appearance:Solid

Color:Pink

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	6-Hydroxy Chlorzoxazone is the major metabolite of the muscle relaxant chlorzoxazone. 6-Hydroxy Chlorzoxazone is a chlorinated benzoxazolone generated by metabolism via the CYP2E1 enzyme in the liver. 6-Hydroxy Chlorzoxazone serves as a reliable marker for assessing CYP2E1 metabolic activity and is used as a reference standard in biochemical research.
In vitro	6-Hydroxy Chlorzoxazone can be used as a metabolite of Chlorzoxazone detectable by HPLC-UV for the in vitro assay of recombinant human CYP2E1 enzyme activity [2].

Chemical Properties

Molecular Weight	185.56
Formula	C₇H₄ClNO₃
Cas No.	1750-45-4
Smiles	O=C1OC2=CC(O)=C(Cl)C=C2N1
Relative Density.	1.649 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (431.13 mM), Sonication is recommended.

Methanol: Slightly Soluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.3891 mL	26.9455 mL	53.8909 mL	269.4546 mL
5 mM	1.0778 mL	5.3891 mL	10.7782 mL	53.8909 mL
10 mM	0.5389 mL	2.6945 mL	5.3891 mL	26.9455 mL
20 mM	0.2695 mL	1.3473 mL	2.6945 mL	13.4727 mL
50 mM	0.1078 mL	0.5389 mL	1.0778 mL	5.3891 mL
100 mM	0.0539 mL	0.2695 mL	0.5389 mL	2.6945 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Keywords

NSC-24955NSC24955NSC 249556-hydroxy Chlorzoxazone6hydroxy Chlorzoxazone6 hydroxy Chlorzoxazone

Related Tags: 6-Hydroxy Chlorzoxazone chemical structure | 6-Hydroxy Chlorzoxazone in vitro | 6-Hydroxy Chlorzoxazone formula | 6-Hydroxy Chlorzoxazone molecular weight