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Selachyl alcohol

🥰Excellent
Catalog No. T75089Cas No. 593-31-7

Selachyl alcohol is an orally active antihypertensive agent with activities similar to antihypertensive neutral renomedullary lipid (ANRL). As an alkylglycerol compound in shark liver oil mixtures, it possesses lung metastasis-inhibiting properties and can be used for cardiovascular disease research.

Selachyl alcohol

Selachyl alcohol

🥰Excellent
Purity: 97.02%
Catalog No. T75089Cas No. 593-31-7
Selachyl alcohol is an orally active antihypertensive agent with activities similar to antihypertensive neutral renomedullary lipid (ANRL). As an alkylglycerol compound in shark liver oil mixtures, it possesses lung metastasis-inhibiting properties and can be used for cardiovascular disease research.
Pack SizePriceAvailabilityQuantity
1 mg$80In Stock
5 mg$196In Stock
10 mg$313In Stock
25 mg$629In Stock
50 mg$886In Stock
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Purity:97.02%
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Product Introduction

Bioactivity
Description
Selachyl alcohol is an orally active antihypertensive agent with activities similar to antihypertensive neutral renomedullary lipid (ANRL). As an alkylglycerol compound in shark liver oil mixtures, it possesses lung metastasis-inhibiting properties and can be used for cardiovascular disease research.
In vivo
Methods: The therapeutic effects of selachyl alcohol (5, 10 mg/kg, oral) or (1 mg/kg, intravenous) were investigated in hypertensive male Sprague-Dawley rats. Results: Selachyl alcohol induced a slow decrease in blood pressure of approximately 60 mmHg that lasted for 20 minutes. It was effective in lowering gastrointestinal blood pressure. [1]
Chemical Properties
Molecular Weight342.56
FormulaC21H42O3
Cas No.593-31-7
SmilesC(CCCCC/C=C\CCCCCCCC)CCOCC(CO)O
ColorTransparent
AppearanceOil
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (233.54 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9192 mL14.5960 mL29.1920 mL145.9598 mL
5 mM0.5838 mL2.9192 mL5.8384 mL29.1920 mL
10 mM0.2919 mL1.4596 mL2.9192 mL14.5960 mL
20 mM0.1460 mL0.7298 mL1.4596 mL7.2980 mL
50 mM0.0584 mL0.2919 mL0.5838 mL2.9192 mL
100 mM0.0292 mL0.1460 mL0.2919 mL1.4596 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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