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Anti-EGFR Antibody-FITC (5D853)

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Catalog No. TMAY-00022F
Alias PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor

Anti-EGFR Antibody-FITC (5D853) is a FITC-conjugated Mouse antibody targeting EGFR. Anti-EGFR Antibody-FITC (5D853) can be used in FCM.

Anti-EGFR Antibody-FITC (5D853)

Anti-EGFR Antibody-FITC (5D853)

😃Good
Catalog No. TMAY-00022FAlias PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor
Anti-EGFR Antibody-FITC (5D853) is a FITC-conjugated Mouse antibody targeting EGFR. Anti-EGFR Antibody-FITC (5D853) can be used in FCM.
Pack SizePriceAvailabilityQuantity
25 T$81 7-10 days
100 T$258 7-10 days
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Product Introduction

Bioactivity
Description
Anti-EGFR Antibody-FITC (5D853) is a FITC-conjugated Mouse antibody targeting EGFR. Anti-EGFR Antibody-FITC (5D853) can be used in FCM.
AliasPIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor
Ig Type
Monoclonal Mouse IgG1
Clone
5D853
Reactivity
Human
Verified Activity
Flow cytometric analysis of EGFR expression on human A431 cells.
Application
FCM
Recommended Dose
1 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human EGFR / HER1 / ErbB1 (rh EGFR / HER1 / ErbB1; TMPY-00742; NP_005219; Met 1-Ser 645) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.09% sodium azide
Research BackgroundAs a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
FITC
Others Formats
Unconjugated/APC/Biotin/PE
Antibody Types Available
5
Antigen Details
Immunogen
Recombinant Human EGFR / HER1 / ErbB1 protein (TMPY-00742)
Antigen Species
Human
Biology Area
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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