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2-chloro Stearic Acid

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Catalog No. T37278Cas No. 56279-49-3

2-chloro Stearic acid is a bioactive fatty acid that accumulates in primary human monocytes and neutrophils as well as murine neutrophils stimulated with phorbol 12-myristate 13-acetate . It induces DNA release from primary human neutrophils. 2-chloro Stearic acid is toxic to C. quinquefasciatus larvae (LC50 = <1 ppm).

2-chloro Stearic Acid

2-chloro Stearic Acid

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Catalog No. T37278Cas No. 56279-49-3
2-chloro Stearic acid is a bioactive fatty acid that accumulates in primary human monocytes and neutrophils as well as murine neutrophils stimulated with phorbol 12-myristate 13-acetate . It induces DNA release from primary human neutrophils. 2-chloro Stearic acid is toxic to C. quinquefasciatus larvae (LC50 = <1 ppm).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$22335 days35 days
5 mg$81635 days35 days
10 mg$1,43035 days35 days
25 mg$3,23035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
2-chloro Stearic acid is a bioactive fatty acid that accumulates in primary human monocytes and neutrophils as well as murine neutrophils stimulated with phorbol 12-myristate 13-acetate . It induces DNA release from primary human neutrophils. 2-chloro Stearic acid is toxic to C. quinquefasciatus larvae (LC50 = <1 ppm).
Chemical Properties
Molecular Weight318.92
FormulaC18H35ClO2
Cas No.56279-49-3
SmilesO=C(O)C(Cl)CCCCCCCCCCCCCCCC
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mg/mL (31.36 mM), Sonication is recommended.
DMF: 30 mg/mL (94.07 mM), Sonication is recommended.
Ethanol: 20 mg/mL (62.71 mM), Sonication is recommended.
Solution Preparation Table
DMSO/Ethanol/DMF
1mg5mg10mg50mg
1 mM3.1356 mL15.6779 mL31.3558 mL156.7791 mL
5 mM0.6271 mL3.1356 mL6.2712 mL31.3558 mL
10 mM0.3136 mL1.5678 mL3.1356 mL15.6779 mL
20 mM0.1568 mL0.7839 mL1.5678 mL7.8390 mL
Ethanol/DMF
1mg5mg10mg50mg
50 mM0.0627 mL0.3136 mL0.6271 mL3.1356 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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