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TG-2-IN-1

Name: TG-2-IN-1
Brand: TargetMol
SKU: T60274
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60274Cas No. 135273-74-4

TG-2-IN-1 is a potent transglutaminase-2 (TGM-2) inhibitor.TG-2-IN-1 is used in the study of cancer, neurological disorders, and immune system disorders.

TG-2-IN-1

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Purity: 98.43%

Catalog No. T60274Cas No. 135273-74-4

TG-2-IN-1 is a potent transglutaminase-2 (TGM-2) inhibitor.TG-2-IN-1 is used in the study of cancer, neurological disorders, and immune system disorders.

Pack Size	Price	Availability
1 mg	$35	In Stock
5 mg	$81	In Stock
10 mg	$128	In Stock
25 mg	$212	In Stock
50 mg	$312	In Stock
100 mg	$463	In Stock
200 mg	$679	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.43%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description

TG-2-IN-1 is a potent transglutaminase-2 (TGM-2) inhibitor.TG-2-IN-1 is used in the study of cancer, neurological disorders, and immune system disorders.

Chemical Properties

Molecular Weight	220.72
Formula	C₈H₁₃ClN₂OS
Cas No.	135273-74-4
Smiles	[Cl-].O=C(C)CSC=1N(C=C[N+]1C)C
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 80 mg/mL (362.45 mM), Sonication is recommended.

DMSO: 20 mg/mL (90.61 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	4.5306 mL	22.6531 mL	45.3063 mL	226.5314 mL
5 mM	0.9061 mL	4.5306 mL	9.0613 mL	45.3063 mL
10 mM	0.4531 mL	2.2653 mL	4.5306 mL	22.6531 mL
20 mM	0.2265 mL	1.1327 mL	2.2653 mL	11.3266 mL
50 mM	0.0906 mL	0.4531 mL	0.9061 mL	4.5306 mL

H2O

	1mg	5mg	10mg	50mg
100 mM	0.0453 mL	0.2265 mL	0.4531 mL	2.2653 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc