Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of some compounds to receive electrons.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 36.00 | |
5 mg | In stock | $ 85.00 | |
10 mg | In stock | $ 126.00 | |
25 mg | In stock | $ 213.00 | |
50 mg | In stock | $ 347.00 | |
100 mg | In stock | $ 580.00 | |
500 mg | In stock | $ 1,260.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 235.00 |
Description | KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of some compounds to receive electrons. |
Targets&IC50 | LOX1:19 μM |
In vitro |
KKII5 (100 μM) has a significant inhibitory effect on lipid peroxidation, with an inhibition rate of 98%.[1] KKII5 interacts with HIS499 of the cavity by forming a π-π stacking interaction between the benzene ring of the molecule and the imidazole ring of HIS499.[1] |
Molecular Weight | 266.36 |
Formula | C16H14N2S |
CAS No. | 6381-55-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 53.27 mg/mL (200 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
KKII5 6381-55-1 Metabolism Lipoxygenase inhibitor inhibit