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BIO8898, a potent inhibitor of the CD40-CD154 interaction, effectively prevents soluble CD40L from binding to CD40-Ig, demonstrating an inhibitory concentration (IC 50) value of 25 µM. Additionally, BIO8898 suppresses CD40L-induced apoptosis [1].
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| 5 mg | Inquiry | Backorder | Backorder | |
| 50 mg | Inquiry | Backorder | Backorder |
| Description | BIO8898, a potent inhibitor of the CD40-CD154 interaction, effectively prevents soluble CD40L from binding to CD40-Ig, demonstrating an inhibitory concentration (IC 50) value of 25 µM. Additionally, BIO8898 suppresses CD40L-induced apoptosis [1]. |
| Targets&IC50 | CD40L:25 μM |
| Molecular Weight | 909.13 |
| Formula | C53H64N8O6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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