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Stamulumab
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Catalog No. T76993Cas No. 705287-60-1
Alias MYO-029, MYO029
Stamulumab (MYO-029) is a high-affinity recombinant human antibody and myostatin neutralising antibody capable of increasing muscle mass in SCID mice. It may be employed in studying various muscular dystrophies, such as BMD, FSHD, and LGMD.
Stamulumab
Stamulumab
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Purity: 95%
Catalog No. T76993Alias MYO-029, MYO029Cas No. 705287-60-1
Stamulumab (MYO-029) is a high-affinity recombinant human antibody and myostatin neutralising antibody capable of increasing muscle mass in SCID mice. It may be employed in studying various muscular dystrophies, such as BMD, FSHD, and LGMD.
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Purity:96.7% (SDS-PAGE); 99.1% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Stamulumab (MYO-029) is a high-affinity recombinant human antibody and myostatin neutralising antibody capable of increasing muscle mass in SCID mice. It may be employed in studying various muscular dystrophies, such as BMD, FSHD, and LGMD. |
| In vivo | Method: Stamulumab (1-10 mg/kg/week, 12 weeks) was administered intraperitoneally to female SCID mice to evaluate its efficacy. Results: Stamulumab dose-dependently increased skeletal muscle mass, with an Emax value of 23%-30% and a Cave50 range of 47-72 nM. [1] |
| Synonyms | MYO-029, MYO029 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | GDF8/Myostatin |
| Molecular Weight | 142.80 kDa |
| Cas No. | 705287-60-1 |
| Isotype | Human IgG1 lambda2 |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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