(Sar1)-Angiotensin II

Name: (Sar1)-Angiotensin II
Brand: TargetMol
SKU: T35834
Rating: 4.5 (1 reviews)

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Catalog No. T35834Cas No. 51833-69-3

Alias (Sar¹)-Angiotensin II

The substitution with Sar at position 1 of angiotensin II resulted in a partial agonistic activity.

(Sar1)-Angiotensin II

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Catalog No. T35834Alias (Sar¹)-Angiotensin IICas No. 51833-69-3

The substitution with Sar at position 1 of angiotensin II resulted in a partial agonistic activity.

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Product Introduction

Bioactivity

Description	The substitution with Sar at position 1 of angiotensin II resulted in a partial agonistic activity.
Synonyms	(Sar¹)-Angiotensin II

Chemical Properties

Molecular Weight	1002.188
Formula	C₄₉H₇₁N₁₃O₁₀
Cas No.	51833-69-3
Smiles	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Relative Density.	no data available
Sequence	H-Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
Sequence Short	GRVYIHPF

Storage & Solubility Information

Storage	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO: Soluble

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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