Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KTX-582 is a potent IRAK4 degrader, exhibiting DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. It efficiently induces apoptosis in MYD88 MT DLBCL and has demonstrated effectiveness in inducing in vivo tumor regressions in a lymphoma model [1] [2] [3].
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Description | KTX-582 is a potent IRAK4 degrader, exhibiting DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. It efficiently induces apoptosis in MYD88 MT DLBCL and has demonstrated effectiveness in inducing in vivo tumor regressions in a lymphoma model [1] [2] [3]. |
Molecular Weight | 872.93 |
Formula | C45H51F3N8O7 |
CAS No. | 2573298-13-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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KTX-582 2573298-13-0 inhibitor inhibit