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Anti-IL-6R Antibody (5X839) (Synonyms: interleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL6Q|...)

Name: Anti-IL-6R Antibody (5X839)
Brand: TargetMol
SKU: TMAY-03209
Rating: 4.5 (1 reviews)

Catalog No. TMAY-03209 Copy Product Info

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Anti-IL-6R Antibody (5X839) is a Rabbit antibody targeting IL-6R. Anti-IL-6R Antibody (5X839) can be used in ELISA(Cap),FCM.

Anti-IL-6R Antibody (5X839)

Copy Product Info

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Catalog No. TMAY-03209

Synonyms interleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL6Q, gp80, CD126

Anti-IL-6R Antibody (5X839) is a Rabbit antibody targeting IL-6R. Anti-IL-6R Antibody (5X839) can be used in ELISA(Cap),FCM.

Anti-IL-6R Antibody
(5X839)

Pack Size	Price	USA Stock	Global Stock	Quantity
20 μL	$93	7-10 days	7-10 days
100 μL	$269	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-IL-6R Antibody (5X839) is a Rabbit antibody targeting IL-6R. Anti-IL-6R Antibody (5X839) can be used in ELISA(Cap),FCM.
Synonyms	interleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL6Q, gp80, CD126
Ig Type	Rabbit IgG
Clone	5X839
Reactivity	Mouse
Specificity	Mouse IL-6R
Verified Activity	Flow cytometric analysis of Mouse IL6Ra(CD126) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse IL6Ra(CD126), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application	ELISA(Cap) FCM
Recommended Dose	FCM: 1:25-1:100; ELISA(Cap): 1:250-1:2000
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-6R / CD126 (rM IL-6R / CD126; TMPY-01214; NP_034689.2; Ile44-Glu357).
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a SIL-6R protein can mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signaling. Through this so-called 'trans-signaling' mechanism, IL-6 can stimulate cells that lack an endogenous mIL-6R. High levels of IL-6 and SIL-6R have been reported in several chronic inflammatory and autoimmune diseases as well as in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

Related Conjugates and Formulations

Conjucates	Unconjugated
Others Formats	APC/PE
Antibody Types Available	3

Antigen Details

Immunogen	Recombinant Protein: Mouse IL-6R / CD126 protein (TMPY-01214)
Antigen Species	Mouse
Biology Area	Neuroinflammation

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

CD-126CD 126

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