Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki of 696 nM, making it suitable for Alzheimer's disease research [1].
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Description | MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki of 696 nM, making it suitable for Alzheimer's disease research [1]. |
Targets&IC50 | Human 5-HT 6 Receptor:696 nM (Ki), MAO-B:96 nM |
In vitro | MAO-B-IN-3 exhibits minimal inhibitory activity against MAO-A with an inhibition rate of 3% at a concentration of 1 μM. The compound demonstrates a Ki value of 696 nM for the 5-HT6 receptor in HEK293 cells stably expressing h5-HT6R [1]. |
Molecular Weight | 387.47 |
Formula | C24H25N3O2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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MAO-B-IN-3 Neuroscience Monoamine Oxidase inhibitor inhibit