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Samalizumab
🥰Excellent
Catalog No. T78295Cas No. 1073059-33-2
Alias ALXN 6000
Samalizumab (ALXN 6000) is a humanized anti-CD200 monoclonal antibody that specifically targets the CD200 immunoregulatory cell surface protein, a member of the immunoglobulin superfamily which functions to dampen excessive immune responses and maintain self-tolerance, thereby establishing Samalizumab as an effective immune checkpoint inhibitor currently under investigation for the treatment of myeloma and B-cell chronic lymphocytic leukemia (CLL).
Samalizumab
Samalizumab
🥰Excellent
Purity: 95%
Catalog No. T78295Alias ALXN 6000Cas No. 1073059-33-2
Samalizumab (ALXN 6000) is a humanized anti-CD200 monoclonal antibody that specifically targets the CD200 immunoregulatory cell surface protein, a member of the immunoglobulin superfamily which functions to dampen excessive immune responses and maintain self-tolerance, thereby establishing Samalizumab as an effective immune checkpoint inhibitor currently under investigation for the treatment of myeloma and B-cell chronic lymphocytic leukemia (CLL).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $247 | In Stock | |
| 5 mg | $647 | In Stock | |
| 10 mg | $1,200 | In Stock |
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Concentration:10.47 mg/mL
Purity:95%
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Product Introduction
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Chemical Properties
| Description | Samalizumab (ALXN 6000) is a humanized anti-CD200 monoclonal antibody that specifically targets the CD200 immunoregulatory cell surface protein, a member of the immunoglobulin superfamily which functions to dampen excessive immune responses and maintain self-tolerance, thereby establishing Samalizumab as an effective immune checkpoint inhibitor currently under investigation for the treatment of myeloma and B-cell chronic lymphocytic leukemia (CLL). |
| In vitro | Samalizumab can specifically bind to the immune checkpoint CD200, block receptor binding and signal transduction, and antagonize CD200-driven immunosuppression, thereby mediating anti-tumor immune responses [1]. |
| Synonyms | ALXN 6000 |
| Cas No. | 1073059-33-2 |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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