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Anti-IFN-beta Antibody (5C41)
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Catalog No. TMAY-01096
Alias interferon, β1, fibroblast, interferon, beta 1, fibroblast, IFN-β
Anti-IFN-beta Antibody (5C41) is a Mouse antibody targeting IFN-beta. Anti-IFN-beta Antibody (5C41) can be used in ELISA.
Anti-IFN-beta Antibody (5C41)
Anti-IFN-beta Antibody (5C41)
😃Good
Catalog No. TMAY-01096Alias interferon, β1, fibroblast, interferon, beta 1, fibroblast, IFN-β
Anti-IFN-beta Antibody (5C41) is a Mouse antibody targeting IFN-beta. Anti-IFN-beta Antibody (5C41) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IFN-beta Antibody (5C41) is a Mouse antibody targeting IFN-beta. Anti-IFN-beta Antibody (5C41) can be used in ELISA. |
| Alias | interferon, β1, fibroblast, interferon, beta 1, fibroblast, IFN-β |
| Ig Type | Monoclonal Mouse IgG2a |
| Clone | 5C41 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IFNB1 / IFN-beta / Interferon beta (rh IFNB1; NP_002167.1Met1-Asn187). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, parasites, and tumor cells. Interferon-beta (IFN beta) is an extracellular protein mediator of host defense and homeostasis. IFN beta has well-established direct antiviral, antiproliferative, and immunomodulatory properties. Recombinant IFN beta is approved for the treatment of relapsing-remitting multiple sclerosis. The recombinant IFN beta protein has the theoretical potential to either treat or causes autoimmune neuromuscular disorders by altering the complicated and delicate balances within the immune system networks. It is the most widely prescribed disease-modifying therapy for multiple sclerosis (MS). Large-scale clinical trials have established the clinical efficacy of IFN beta in reducing relapses and slowing disease progression in relapsing-remitting MS. IFN beta therapy was shown to be comparably beneficial for opticospinal MS (OSMS) and conventional MS in Japanese. IFN beta is effective in reducing relapses in secondary progressive MS and may have a modest effect in slowing disability progression. In addition to the common antiviral activity, IFN beta also induces increased production of the p53 gene product which promotes apoptosis and thus has a therapeutic effect against certain cancers. The role of IFN-beta in bone metabolism could warrant its systematic evaluation as a potential adjunct to therapeutic regimens of osteolytic diseases. Furthermore, IFN beta might play a beneficial role in the development of chronic progressive CNS inflammation.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human IFNB1 / IFN-beta / Interferon beta protein |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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