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Anti-Cystatin B Antibody (3X196) (Synonyms: ULD, STFB, PME, EPM1A, EPM1, cystatin B (stefin B), CST6)
Catalog No. TMAY-00828 Copy Product Info
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Anti-Cystatin B Antibody (3X196) is a Mouse antibody targeting Cystatin B. Anti-Cystatin B Antibody (3X196) can be used in ELISA(Cap).
Anti-Cystatin B Antibody (3X196)
Copy Product Info🥰Excellent
Catalog No. TMAY-00828
Synonyms ULD, STFB, PME, EPM1A, EPM1, cystatin B (stefin B), CST6
Anti-Cystatin B Antibody (3X196) is a Mouse antibody targeting Cystatin B. Anti-Cystatin B Antibody (3X196) can be used in ELISA(Cap).
Anti-Cystatin B Antibody
(3X196)
(3X196)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μL | $68 | 7-10 days | 7-10 days | |
| 100 μL | $198 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-Cystatin B Antibody (3X196) is a Mouse antibody targeting Cystatin B. Anti-Cystatin B Antibody (3X196) can be used in ELISA(Cap). |
| Synonyms | ULD, STFB, PME, EPM1A, EPM1, cystatin B (stefin B), CST6 |
| Ig Type | Mouse IgG1 |
| Clone | 3X196 |
| Reactivity | Human |
| Specificity | Human Cystatin B |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Cystatin B (rh Cystatin B; TMPY-02090; P04080; Met2-Phe98). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS with 10% Trehalose, 0.02% Tween 80, pH7.0 |
| Research Background | Cystatin-B, also known as CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB and CST6, is a cytoplasm and nucleus protein which belongs to thecystatin family. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes. Defects in Cystatin-B / CSTB are the cause of progressive myoclonic epilepsy type 1 (EPM1) which is an autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures. The cystatins are a family of cysteine protease inhibitors with homology to chicken cystatin. Cystatins are physiological inhibitors of cysteine proteinases which are widely distributed in human tissues and fluids. Cystatins typically comprise about 115 amino acids, are largely acidic, contain four conserved cysteine residues known to form two disulfide bonds. Cystatins may be glycosylated and / or phosphorylated, with similarity to fetuins, kininogens, stefins, histidine-rich glycoproteins and cystatin-related proteins. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired inhibitory activity. Cystatins mainly inhibit peptidases belonging to peptidase families C1 (papain family) and C13 (legumain family). |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Cystatin B Protein (TMPY-02090) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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