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Anti-FGFRL1 Antibody (4C661) (Synonyms: fibroblast growth factor receptor-like 1, FGFR5γ, FGFR5β, FGFR5gamma|...)
Catalog No. TMAY-03161 Copy Product Info
🥰Excellent
Anti-FGFRL1 Antibody (4C661) is a Rabbit antibody targeting FGFRL1. Anti-FGFRL1 Antibody (4C661) can be used in IP,WB.
Anti-FGFRL1 Antibody (4C661)
Copy Product Info🥰Excellent
Catalog No. TMAY-03161
Synonyms fibroblast growth factor receptor-like 1, FGFR5γ, FGFR5β, FGFR5gamma, FGFR5beta, FGFR5
Anti-FGFRL1 Antibody (4C661) is a Rabbit antibody targeting FGFRL1. Anti-FGFRL1 Antibody (4C661) can be used in IP,WB.
Anti-FGFRL1 Antibody
(4C661)
(4C661)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-FGFRL1 Antibody (4C661) is a Rabbit antibody targeting FGFRL1. Anti-FGFRL1 Antibody (4C661) can be used in IP,WB. |
| Synonyms | fibroblast growth factor receptor-like 1, FGFR5γ, FGFR5β, FGFR5gamma, FGFR5beta, FGFR5 |
| Ig Type | Rabbit IgG |
| Clone | 4C661 |
| Reactivity | Mouse |
| Specificity | Mouse FGFRL1 |
| Verified Activity | 1. Anti-FGFRL1 rabbit monoclonal antibody at 1:500 dilution. -Lane A: 293T Whole Cell Lysate. -Lane B: HepG2 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:55 kDa. -Observed band size:62 kDa. 2. Mouse FGFRL1 was immunoprecipitated using: -Lane A:0.5 mg Hela Whole Cell Lysate. -2 µL anti-Mouse FGFRL1 rabbit monoclonal antibody and 15 μl of 50 % Protein G agarose. -Primary antibody: -Anti-Mouse FGFRL1 rabbit monoclonal antibody, at 1:100 dilution. -Secondary antibody: -Clean-Blotô IP Detection Reagent (HRP) at 1:1000 dilution. -Developed using the DAB staining technique. -Performed under reducing conditions. -Predicted band size: 55 kDa. -Observed band size: 70 kDa |
| Application | |
| Recommended Dose | WB: 1:500-1:2000; IP: 4-6 μL/mg of lysate |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse FGFRL1 / FGFR5 (rM FGFRL1 / FGFR5; TMPY-01360; NP_473412.1; Met1-Pro374). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Fibroblast growth factor receptor-like 1 (FGFRL1) also known as Fibroblast growth factor receptor 5 (FGFR5), is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A unique feature of FGFRL1/FGFR5 is that it does not contain an intracellular tyrosine kinase domain. Some muscle types, including the muscles of the tongue and the diaphragm, express FGFRL1/FGFR5 at relatively high level. In contrast, the heart and the skeletal muscles of the limbs, as well as many other organs (brain, lung, liver, kidney, gut) express Fgfrl1 only at basal level. It is conceivable that FGFRL1/FGFR5 interacts with other Fgfrs, which are expressed in cartilage and muscle, to modulate FGF signaling.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse FGFRL1 / FGFR5 protein (TMPY-01360) |
| Antigen Species | Mouse |
| Biology Area | Receptor Tyrosine Kinases (RTKs) |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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