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IL-17 modulator 4

🥰Excellent
Catalog No. T36526Cas No. 2446803-65-0

IL-17 modulator 4 is a prodrug of IL-17 modulator 1, which acts as a potent modulator of IL-17.

IL-17 modulator 4

IL-17 modulator 4

🥰Excellent
Purity: 99.59%
Catalog No. T36526Cas No. 2446803-65-0
IL-17 modulator 4 is a prodrug of IL-17 modulator 1, which acts as a potent modulator of IL-17.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$278In StockIn Stock
5 mg$689In StockIn Stock
10 mg$1,090In StockIn Stock
25 mg$1,970In StockIn Stock
50 mg$3,250In StockIn Stock
1 mL x 10 mM (in DMSO)$735In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.59%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
IL-17 modulator 4 is a prodrug of IL-17 modulator 1, which acts as a potent modulator of IL-17.
Chemical Properties
Molecular Weight474.6
FormulaC27H34N6O2
Cas No.2446803-65-0
SmilesCC(C)n1nccc1C(=O)N[C@@H](C(C1CC1)C1CC1)C(=O)Nc1ccc(cc1)-c1c(C)n[nH]c1C
Relative Density.1.35 g/cm3 (Predicted)
Storage & Solubility Information
StorageIn solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 270 mg/mL (568.9 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1070 mL10.5352 mL21.0704 mL105.3519 mL
5 mM0.4214 mL2.1070 mL4.2141 mL21.0704 mL
10 mM0.2107 mL1.0535 mL2.1070 mL10.5352 mL
20 mM0.1054 mL0.5268 mL1.0535 mL5.2676 mL
50 mM0.0421 mL0.2107 mL0.4214 mL2.1070 mL
100 mM0.0211 mL0.1054 mL0.2107 mL1.0535 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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