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(Z)-Ligustilide

🥰Excellent
Catalog No. T13670LCas No. 81944-09-4
Alias Ligustilide A, cis-Ligustilide

(Z)-Ligustilide (Ligustilide A) , an active ingredient isolated from the medicinal plants Angelica acutiloba and Cnidium officinale, inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation.

(Z)-Ligustilide
Other Forms of (Z)-Ligustilide:

(Z)-Ligustilide

🥰Excellent
Purity: 98.81%
Catalog No. T13670LAlias Ligustilide A, cis-LigustilideCas No. 81944-09-4
(Z)-Ligustilide (Ligustilide A) , an active ingredient isolated from the medicinal plants Angelica acutiloba and Cnidium officinale, inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation.
Pack SizePriceAvailabilityQuantity
2 mg$30In Stock
5 mg$44In Stock
10 mg$78In Stock
25 mg$140In Stock
50 mg$210In Stock
100 mg$315In Stock
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Batch Information

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Purity:98.81%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
(Z)-Ligustilide (Ligustilide A) , an active ingredient isolated from the medicinal plants Angelica acutiloba and Cnidium officinale, inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation.
SynonymsLigustilide A, cis-Ligustilide
Chemical Properties
Molecular Weight190.24
FormulaC12H14O2
Cas No.81944-09-4
SmilesCCC/C=C\1/C2=C(C=CCC2)C(=O)O1
Relative Density.1.10 g/cm3 at 20℃
Storage & Solubility Information
Storagekeep away from direct sunlight,store under nitrogen,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (525.65 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (21.03 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.2565 mL26.2826 mL52.5652 mL262.8259 mL
5 mM1.0513 mL5.2565 mL10.5130 mL52.5652 mL
10 mM0.5257 mL2.6283 mL5.2565 mL26.2826 mL
20 mM0.2628 mL1.3141 mL2.6283 mL13.1413 mL
50 mM0.1051 mL0.5257 mL1.0513 mL5.2565 mL
100 mM0.0526 mL0.2628 mL0.5257 mL2.6283 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

LigustilideInhibitorinhibitbacterialBacterial(Z)-Ligustilide(Z)Ligustilide(Z) Ligustilide
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