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GSK1820795A

Name: GSK1820795A
Brand: TargetMol
SKU: T64011
Price: 163 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T64011 Copy Product Info

Purity: 99.78%

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GSK1820795A is a selective G2A/GPR132a antagonist and a telmisartan analog. GSK1820795A also exhibits angiotensin II receptor antagonist activity and partial PPARγ agonist activity. GSK1820795A effectively blocks the activating effects of N-acylamides on yeast cells expressing hGPR132a.

Cas No. 2650253-86-2

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Pack Size	Price	USA Stock	Global Stock
1 mg	$163	-	In Stock
5 mg	$419	-	In Stock
10 mg	$679	-	In Stock
25 mg	$1,360	-	In Stock
50 mg	$1,980	-	In Stock
100 mg	$2,500	-	In Stock
1 mL x 10 mM (in DMSO)	$526	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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Custom-made molecule. TargetMol’s expert synthesis team delivers cost-effective solutions. Contact us for inquiries. Committed to serving you.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.78%

Appearance:Solid

Color:White

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Product Introduction

Bioactivity

Description	GSK1820795A is a selective G2A/GPR132a antagonist and a telmisartan analog. GSK1820795A also exhibits angiotensin II receptor antagonist activity and partial PPARγ agonist activity. GSK1820795A effectively blocks the activating effects of N-acylamides on yeast cells expressing hGPR132a.
Targets & IC50	PPARγ (mouse):0.27 μM (EC50), AT1 Receptor:0.006 μM, PPARγ (human):0.25 μM (EC50)

Chemical Properties

Molecular Weight	566.70
Formula	C₃₅H₃₄N₈
Cas No.	2650253-86-2
Smiles	N1=NNC(=N1)C=2C=CC=CC2C=3C=CC(=CC3)CC4=C5C=C(C=CC5=NN4CCC)C6=NC=7C=CC=CC7N6CCCC

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (141.17 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7646 mL	8.8230 mL	17.6460 mL	88.2301 mL
5 mM	0.3529 mL	1.7646 mL	3.5292 mL	17.6460 mL
10 mM	0.1765 mL	0.8823 mL	1.7646 mL	8.8230 mL
20 mM	0.0882 mL	0.4412 mL	0.8823 mL	4.4115 mL
50 mM	0.0353 mL	0.1765 mL	0.3529 mL	1.7646 mL
100 mM	0.0176 mL	0.0882 mL	0.1765 mL	0.8823 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Related Tags: GSK1820795A chemical structure | GSK1820795A formula | GSK1820795A molecular weight